| SRS | <abbreviation> Slow-reacting substance. (05 Mar 2000) |
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| srs-a | A group of leukotrienes (ltc4, ltd4, and lte4) that is the major mediator of bronchial constriction and other allergic reactions. Earlier studies had described a "slow-reacting substance of anaphylaxis" released from guinea pig and cat lung by cobra venom, and in guinea pig lung after anaphylactic shock. The relationship between srs-a and members of the leukotriene family was established following publication of the uv spectrum of purified srs-a, that showed the presence of the conjugated triene. (12 Dec 1998) |