| simvastatin | <chemical> A derivative of lovastatin and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase (hydroxymethylglutaryl CoA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic ldl receptors, it increases breakdown of ldl-cholesterol (lipoproteins, ldl cholesterol). Pharmacological action: anticholesteraemic agents, antilipaemic agents, hydroxymethylglutaryl-CoA reductase inhibitors. (12 Dec 1998) |
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| TAB vaccine | A suspension of killed typhoid and paratyphoid A and B bacilli. See: typhoid vaccine. Synonym: TAB vaccine. (05 Mar 2000) |
| peptolide SDZ 214-103 synthetase | <chemical> Catalyses at least 39 partial reaction steps in the synthesis of sdz 214-103 by the fungus cylindrotrichum oligospermum Chemical name: synthetase, peptolide Synonym: sdz 214-103 synthetase (26 Jun 1999) |
| SDZ 90-215 synthetase | <enzyme> Catalyses the synthesis of sdz 90-215 in the fungus septoria Registry number: EC 6.3.2.- (26 Jun 1999) |