| tumor | 1. <oncology> An abnormal mass of tissue that results from excessive cell division that is uncontrolled and progressive, also called a neoplasm. Tumours perform no useful body function. They may be either benign (not cancerous) or malignant. 2. Swelling, one of the cardinal signs of inflammations, morbid enlargement. Origin: L. Tumere = to swell (12 May 1997) |
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| tumor marker | <investigation, oncology> A substance in the body that usually indicates the presence of cancer. These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples. Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH). They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids. (18 Jul 2002) |
| tumor necrosis factor | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |
| Rous-associated virus | A leukaemia virus of the leukosis-sarcoma complex which by phenotypic mixing with a defective (noninfectious) strain of Rous sarcoma virus effects production of infectious sarcoma virus with envelope antigenicity of the RAV. (05 Mar 2000) |
| Rous, F Peyton | <person> U.S. Pathologist and Nobel laureate, 1879-1970. See: Rous sarcoma, Rous sarcoma virus, Rous tumour, Rous-associated virus. (05 Mar 2000) |
| Rous sarcoma | <tumour> A fibrosarcoma, originally observed in a Plymouth Rock hen, now thought to be an expression of infection by certain viruses of the avian leukosis-sarcoma complex in the family Retroviridae. Synonym: avian sarcoma, Rous tumour. (05 Mar 2000) |
| Rous sarcoma virus | <virology> The virus responsible for the classic first cell free transmission of a solid tumour, the chicken sarcoma, first reported by Rous in 1911. An avian C type oncorna virus, original source of the src oncogene. (18 Nov 1997) |
| Rous sarcoma virus protease | <enzyme> Has been sequenced; crystallographic structure has been determined Registry number: EC 3.4.23.- Synonym: protease, rous sarcoma virus, rous sarcoma virus aspartic protease (26 Jun 1999) |
| Rous tumour | <tumour> A fibrosarcoma, originally observed in a Plymouth Rock hen, now thought to be an expression of infection by certain viruses of the avian leukosis-sarcoma complex in the family Retroviridae. Synonym: avian sarcoma, Rous tumour. (05 Mar 2000) |