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Rous sarcoma virus protease <enzyme> Has been sequenced; crystallographic structure has been determined
Registry number: EC 3.4.23.-
Synonym: protease, rous sarcoma virus, rous sarcoma virus aspartic protease
(26 Jun 1999)
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Rous sarcoma virus <virology> The virus responsible for the classic first cell free transmission of a solid tumour, the chicken sarcoma, first reported by Rous in 1911. An avian C type oncorna virus, original source of the src oncogene.
(18 Nov 1997)
Rous sarcoma <tumour> A fibrosarcoma, originally observed in a Plymouth Rock hen, now thought to be an expression of infection by certain viruses of the avian leukosis-sarcoma complex in the family Retroviridae.
Synonym: avian sarcoma, Rous tumour.
(05 Mar 2000)
Rous-associated virus A leukaemia virus of the leukosis-sarcoma complex which by phenotypic mixing with a defective (noninfectious) strain of Rous sarcoma virus effects production of infectious sarcoma virus with envelope antigenicity of the RAV.
(05 Mar 2000)
Kaposi sarcoma associated herpesvirus protease <enzyme> Genbank af010430
Registry number: EC 3.4.21.-
Synonym: kshv protease, human herpesvirus 8 protease
(26 Jun 1999)
Rous, F Peyton <person> U.S. Pathologist and Nobel laureate, 1879-1970.
See: Rous sarcoma, Rous sarcoma virus, Rous tumour, Rous-associated virus.
(05 Mar 2000)
Rous tumour <tumour> A fibrosarcoma, originally observed in a Plymouth Rock hen, now thought to be an expression of infection by certain viruses of the avian leukosis-sarcoma complex in the family Retroviridae.
Synonym: avian sarcoma, Rous tumour.
(05 Mar 2000)
avian leukosis-sarcoma virus avian leukosis-sarcoma complex
avian sarcoma virus avian leukosis-sarcoma complex
Moloney murine sarcoma virus <molecular biology, virology> Replication defective retrovirus, source of the oncogene v mos, responsible for inducing fibrosarcomas in vivo and transforming cells in culture.
(18 Nov 1997)
moloney sarcoma virus A replication-defective murine sarcoma virus (sarcoma viruses, murine) isolated from a rhabdomyosarcoma by moloney in 1966.
(12 Dec 1998)
murine sarcoma virus A seemingly defective retrovirus that produces sarcomas in mice when growing in the presence of a "helper" virus; e.g., mouse leukaemia virus.
(05 Mar 2000)
porcine sarcoma virus A retrovirus causing sarcoma in swine.
(05 Mar 2000)
Harvey sarcoma virus <oncogene> One of a family of oncogenes, first identified as transforming genes of Harvey and Kirsten murine sarcoma viruses. (Name from rat sarcoma because Harvey virus, though a mouse virus, obtained its transforming gene during passage in a rat). Transforming protein coded is p21ras, a GTP-binding protein with GTPase activity, that resembles regulatory G-proteins.
(18 Nov 1997)
sarcoma virus <virology> Virus that causes tumours originating from cells of connective tissue such as fibroblasts.
See: Rous sarcoma virus, src.
(18 Nov 1997)
sarcoma virus, feline A species of mammalian type c retroviruses (retroviruses type c, mammalian) isolated from fibrosarcoma in cats. The virus is actually a recombinant feline leukaemia virus (felv) where part of the genome has been replaced by cellular oncogenes. It is unique to individuals and not transmitted naturally to other cats. Fesv is replication defective and requires felv to reproduce.
(12 Dec 1998)
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