| Rieder's lymphocyte | An abnormal form of lymphocyte that has a greatly indented (or lobed), slightly twisted nucleus; such cells are usually observed in certain examples of chronic lymphocytic leukaemia. (05 Mar 2000) |
|---|---|
| leukemia | <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is classified according of the type leucocyte most prominently involved. (18 Nov 1997) |
| Rieder cell leukaemia | A special form of acute granulocytic leukaemia in which the affected tissues and the circulating blood contain relatively large numbers of atypical myeloblasts (i.e., Rieder cells) that have the usual, faintly granular, immature type of cytoplasm, and a bizarre, comparatively mature nucleus with several wide and deep indentations (suggestive of lobulation). (05 Mar 2000) |
| lymphocyte lymphocyte | A type of non-granular antibodies. (09 Oct 1997) |
| Rieder cells | Abnormal myeloblasts (12 to 20 um in diameter) in which the nucleus may be widely and deeply indented (i.e., suggestive of lobulation), or may actually be a bi-or multi-lobate structure; such cell's are frequently observed in acute leukaemia, and probably represent a more rapid maturation of the nucleus than that of the cytoplasm. (05 Mar 2000) |
| Rieder, Hermann | <person> German pathologist, 1858-1932. See: Rieder cells, Rieder cell leukaemia, Rieder's lymphocyte. (05 Mar 2000) |
| antigens, differentiation, b-lymphocyte | Membrane antigens associated with maturation stages of B-lymphocytes, often expressed in tumours of B-cell origin. (12 Dec 1998) |
| antigens, differentiation, t-lymphocyte | Antigens expressed on the cell membrane of T-lymphocytes during differentiation, activation, and normal and neoplastic transformation. Their phenotypic characterization is important in differential diagnosis and studies of thymic ontogeny and T-cell function. (12 Dec 1998) |
| bare lymphocyte syndrome | <syndrome> Absence of HLA antigens on peripheral mononuclear cells, which may result in immunodeficiency. (05 Mar 2000) |
| B lymphocyte | <haematology, immunology> An immunologically important lymphocyte, produced by the bone marrow, that is responsible for the production of immunoglobulins, it is the precursor of the plasma cell. The surface markers can be used to detect and differentiate chronic lymphocytic leukaemia from acute lymphocytic leukaemia. (13 Nov 1997) |
| b-lymphocyte subsets | A classification of B-lymphocytes based on structurally or functionally different populations of cells. (12 Dec 1998) |
| gene rearrangement, b-lymphocyte | Ordered rearrangement of b-lymphocyte variable gene regions coding for the immunoglobulin chains, thereby contributing to antibody diversity. It occurs during the differentiation of the immature b-lymphocyte. (12 Dec 1998) |
| gene rearrangement, b-lymphocyte, heavy chain | Ordered rearrangement of b-lymphocyte variable gene regions thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the immature b-lymphocyte. (12 Dec 1998) |
| gene rearrangement, b-lymphocyte, light chain | Ordered rearrangement of b-lymphocyte variable gene regions coding for the kappa or lambda light chains, thereby contributing to antibody diversity. It occurs during the second stage of differentiation of the immature b-lymphocyte. (12 Dec 1998) |
| gene rearrangement, t-lymphocyte | Ordered rearrangement of T-cell variable gene regions coding for the antigen receptors. (12 Dec 1998) |