| gene products, rev | Trans-acting nuclear proteins whose functional expression are required for HIV viral replication. Specifically, the rev gene products are required for processing and translation of the HIV gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. Rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (car) in env, also known as the rev-responsive element (rre), is responsive to the rev gene product. Rev is short for regulator of virion. (12 Dec 1998) |
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| genes, rev | DNA sequences that form the coding region for a protein that regulates the expression of the viral structural and regulatory proteins in human immunodeficiency virus (HIV). Rev is short for regulator of virion. (12 Dec 1998) |
| rev | <molecular biology> A regulatory protein produced by HIV within infected cells. Rev helps transport HIV RNA sequences (messenger RNA) out from the nucleus into the cells cytoplasm, where it directs construction of proteins for new virus particles. (11 Jan 1998) |
| Placido da Costa, Antonio | <person> Portuguese ophthalmologist, 1848-1916. See: Placido da Costa's disk. (05 Mar 2000) |
| Placido da Costa's disk | <instrument> An instrument marked with lines or circles by means of which the corneal reflex can be observed. Synonym: Placido da Costa's disk. Origin: kerato-+ G. Skopeo, to examine (05 Mar 2000) |
| costa | <microbiology> Rod shaped intracellular organelle lying below the undulating membrane of Trichomonas. Generates active bending associated with local loss of birefringence at the bending zone, probably as a result of conformational change in the longitudinal lamellae. Major protein approximately 90 kD. (10 Nov 1998) |
| costa cervicalis | A rib which arises from the seventh cervical vertebrae (above the normal first rib). Occurs in only about 0.5% of people. May cause nerve and artery problems. (12 Dec 1998) |