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gold sol test An obsolete, non-specific test for altered proteins in spinal fluid. As originally used by Lange in 1912, the test was thought to be specific for neurosyphilis; however, this proved to be incorrect. Dilutions of spinal fluid are made in saline and to these a colloidal gold solution is added; if altered proteins are present, there is a colour change or precipitate formed. at present, its chief use is to demonstrate cerebrospinal fluid protein abnormalities in multiple sclerosis.
Synonym: gold sol test, Zsigmondy's test.
(05 Mar 2000)
sol 1. The sun.
2. <chemistry> Gold; so called from its brilliancy, colour, and value.
Origin: L.
Source: Websters Dictionary
(01 Mar 1998)
sol gel transformation Transition between more fluid cytoplasm (endoplasm) and stiffer gel like ectoplasm proposed as a mechanism for amoeboid locomotion: since the endoplasm cannot really be considered a simple fluid and has visco elastic properties like a gel, the term is misleading.
(18 Nov 1997)
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