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pyrazinamide Pyrazinamide is most active during the first 2(3) months of therapy. The daily dose for adults is 20-30 mg/kg and for children 30-40 mg/kg, to a maximum of 2500 mg. The intermittent dose is 50-70 mg/kg for both adults and children, with an upper limit of 3500 mg. Pyrazinamide may be used during pregnancy.
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