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genetic code <molecular biology> Relationship between the sequence of bases in nucleic acid and the order of amino acids in the polypeptide synthesised from it. A sequence of three nucleic acid bases (a triplet) acts as a codeword (codon) for one amino acid.
(18 Nov 1997)
code The genetic code is the correspondence between the triplet of bases in DNA with the amino acids. The discovery of the genetic code clearly ranks as one of the premiere events of what has been called the Golden Age of Biology (and Medicine).
(12 Dec 1998)
soundex code A sequence of letters used for recording names phonetically, especially in record linkage.
(05 Mar 2000)
Strickland code <zoology> A code of nomenclature for taxonomic classification prepared by a committee of the British Association for the Advancement of Science, first published in 1842.
(09 Jan 1998)
degenerate code <molecular biology> The fact that in most cases in the genetic code used by all life on Earth, one particular amino acid is specified by more than one three-base combination of the four nitrogenous bases (called a codon).
There are enough different codons to specify 64 different amino acids, but there are in actuality only 20 amino acids (and three stop codons) used in the making of proteins.
(09 Oct 1997)
International Code of Zoological Nomenclature <zoology> An Authoritative document containing a system of rules and recommendations to be followed in giving a scientific name to an animal or animal group. Adopted by the International Congresses of Zoology and Administered by the International Commission on Zoological Nomenclature. The most recent version of the Code, adopted in principle by the 20th General Assembly of the International Union of Biological Sciences at Helsinki in 1979, was approved by the ICZN late in 1983. With minor exceptions it retains the same format as the first two editions. Minor amendments for immediate incorporation are published in Bulletin Zoological Nomenclature as Declarations to remain in force until ratified or rejected by future congresses.
(09 Jan 1998)
uniform mechanical code (UMC) A code sponsored by the International Association of Plumbing and Mechanical Officials and the International Conference of Building Officials, adopted and amended by the Oregon Department of Commerce. The UMC contains requirements for the installation and maintenance of heating, ventilating, cooling, and refrigeration systems.
(05 Dec 1998)
acetoacetyl-acyl carrier protein synthase <enzyme> E coli enzyme, that catalyses condensation of malonyl-acyl carrier protein plus acetyl-acyl carrier protein; not inhibited by cerulenin
Registry number: EC 2.3.1.-
Synonym: acetoacetyl-acp synthase
(26 Jun 1999)
acid soluble spore protein <molecular biology> A DNA binding protein in the spores of some bacteria, thought to stabilise the DNA in an A configuration, so protecting it from cleavage by enzymes or UV light.
(18 Nov 1997)
acute-phase protein <haematology> These plasma proteins (in addition to fibrinogen) increase 25% or more in response to inflammation and injury are under direct control of interleukin-6 (IL-6) (hepatocyte-stimulating factor).
Other proteins which increase are ceruloplasmin, C3 and C4 which increase 50% or more; alpha-1 acid glycoprotein, alpha-1 antitrypsin, haptoglobin and fibrinogen (the major determinant of viscosity 1 ) which increase two- to fourfold; C-reactive protein (CRP) and serum amyloid A which increase several hundred-fold.
Despite long-held clinical opinion to the contrary, available data indicate that neither ESR nor measurement of specific acute-phase reactants are useful in excluding underlying infection or inflammation regardless of the pretest probability.
These proteins are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. They can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumour markers.
See also: amyloid, c-reactive protein, erythrocyte sedimentation rate, viscosity.
(25 Jun 1999)
acyl-(acyl-carrier-protein)-phospholipid acyltransferase <enzyme> Catalyses the formation of phosphatidylethanolamine from acyl-acyl carrier protein and 2-acyl-sn-glycero-3-phosphoethanolamine
Registry number: EC 2.3.1.40
Synonym: 2-acyl-gpe acyltransferase, 2-acylglycerophosphoethanolamine acyltransferase
(26 Jun 1999)
acyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferase <enzyme> E coli enzyme involved in lipid a biosynthesis; uses beta-hydroxymyristoyl-acyl carrier protein to form udp-3-monoacyl-n-acetylglucosamine; amino acid sequence given in second source
Registry number: EC 2.3.1.129
Synonym: udp-aguatransferase, lpxa protein, udp-n-acetylglucosamine-3-acyltransferase, udp-n-acetylglucosamine 3-o-acyltransferase, udp-3-o-(r-3-hydroxymyristoyl)glucosamine-n-acyltransferase, lpxd protein, fira gene product, fira protein
(26 Jun 1999)
acyl carrier protein <protein> A small (77 peptides long) protein which binds six other enzymes involved in fatty acid synthesis. It was first isolated in E. Coli bacteria.
(09 Oct 1997)
acyl carrier protein acylase <enzyme> From E coli
Registry number: EC 2.3.1.-
Synonym: acp acylase
(26 Jun 1999)
acyl protein synthetase <enzyme> Component of the fatty acid reductase complex of luminescent bacteria
Registry number: EC 2.3.1.-
Synonym: luxe gene product, fatty acyl-protein synthetase
(26 Jun 1999)
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