| progesterone | <biochemistry, gynaecology> Produced in the corpus luteum, as an antagonist of oestrogens. Promotes proliferation of uterine mucosa and the implantation of the blastocyst, prevents further follicular development. (18 Nov 1997) |
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| progesterone 20-keto-reductase | <enzyme> Rat liver microsome enzyme requires NADPH to form the 20beta alcohol, also forms 20alpha oh using NADH Registry number: EC 1.1.1.- Synonym: progesterone 20-reductase, progesterone 20-beta reductase (26 Jun 1999) |
| progesterone 5 alpha-reductase | <enzyme> Do not confuse this with progesterone reductase which is a 3 beta-hydroxysteroid dehydrogenase Registry number: EC 1.3.1.30 (26 Jun 1999) |
| progesterone 5 beta-reductase | <enzyme> A stereospecific enzyme; forms 5 beta-pregnane-3,20-dione from progesterone; see also progesterone 5 alpha-reductase Registry number: EC 1.3.1.- (26 Jun 1999) |
| progesterone receptor assay | The progesterone receptor test (PgR assay) checks the tumour for its hormone status. (16 Dec 1997) |
| progesterone reductase | <enzyme> An enzyme that catalyses the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of NAD. It converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione.45. Chemical name: 3 beta-Hydroxy-delta(5)-steroid:NAD+ 3-oxidoreductase Registry number: EC 1.1.1.145 (12 Dec 1998) |
| progesterone unit | The progestational activity of 1 mg of unit of progestational activity; standard preparation of pure progesterone. See: Clauberg test, Corner-Allen unit. Synonym: corpus luteum hormone unit, unit of luteinizing activity. (05 Mar 2000) |
| progesterone-11HS-horseradish peroxidase | <chemical> Used as a tracer in an immunoassay for progesterone Synonym: p-11hs-hrp, progesterone-11hs-hrp (26 Jun 1999) |
| progesterone-3-(O-carboxymethyl oxime)-horseradish peroxidase | <chemical> Used as a tracer in an immunoassay for progesterone Synonym: progesterone-3-(o-carboxymethyl oxime)-hrp, p-3cmo-hrp (26 Jun 1999) |
| progesterone-6-hydroxylase | <enzyme> Cytochrome p-450 2c3 with valine at position 364 which confers 6beta-hydroxylase activity; see also record for cyp2c3 gene product Registry number: EC 1.14.99.- Synonym: progesterone 6beta-hydroxylase, cytochrome p450 2c3v (26 Jun 1999) |
| progesterone-binding globulin | A glycoprotein migrating as alpha 1-globulin, molecular weight 70,000 to 120,000. The protein, which is present in increased amounts in the plasma during pregnancy, binds mainly progesterone, with other steroids including testosterone competing weakly. (12 Dec 1998) |
| receptors, progesterone | Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. There are two kinds of progesterone receptors, a and b. Both are induced by oestrogen and have short half-lives. (12 Dec 1998) |
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| hormone, progesterone | A female hormone, progesterone is the principal progestational hormone. Progestational hormones prepare the uterus (the womb) to receive and sustain the fertilised egg. (12 Dec 1998) |