| progestational | 1. Favouring pregnancy; conducive to gestation; capable of stimulating the uterine changes essential for implantation and growth of a fertilised ovum. 2. Referring to progesterone, or to a drug with progesterone-like properties. (05 Mar 2000) |
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| progestational hormone | <biochemistry, gynaecology> Produced in the corpus luteum, as an antagonist of oestrogens. Promotes proliferation of uterine mucosa and the implantation of the blastocyst, prevents further follicular development. (18 Nov 1997) |
| progestational hormones | A class of sex hormones associated with certain changes in the uterus and vagina during the menstrual cycle. They are necessary for the development of mammary tissue and for the maintenance of pregnancy. (12 Dec 1998) |
| progestational hormones, synthetic | Compounds obtained by chemical synthesis that possess progestational activity, but differ in structure from naturally occurring progestational hormones. (12 Dec 1998) |
| progesterone | <biochemistry, gynaecology> Produced in the corpus luteum, as an antagonist of oestrogens. Promotes proliferation of uterine mucosa and the implantation of the blastocyst, prevents further follicular development. (18 Nov 1997) |
| progesterone 20-keto-reductase | <enzyme> Rat liver microsome enzyme requires NADPH to form the 20beta alcohol, also forms 20alpha oh using NADH Registry number: EC 1.1.1.- Synonym: progesterone 20-reductase, progesterone 20-beta reductase (26 Jun 1999) |
| progesterone 5 alpha-reductase | <enzyme> Do not confuse this with progesterone reductase which is a 3 beta-hydroxysteroid dehydrogenase Registry number: EC 1.3.1.30 (26 Jun 1999) |
| progesterone 5 beta-reductase | <enzyme> A stereospecific enzyme; forms 5 beta-pregnane-3,20-dione from progesterone; see also progesterone 5 alpha-reductase Registry number: EC 1.3.1.- (26 Jun 1999) |
| progesterone receptor assay | The progesterone receptor test (PgR assay) checks the tumour for its hormone status. (16 Dec 1997) |
| progesterone reductase | <enzyme> An enzyme that catalyses the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of NAD. It converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione.45. Chemical name: 3 beta-Hydroxy-delta(5)-steroid:NAD+ 3-oxidoreductase Registry number: EC 1.1.1.145 (12 Dec 1998) |
| progesterone unit | The progestational activity of 1 mg of unit of progestational activity; standard preparation of pure progesterone. See: Clauberg test, Corner-Allen unit. Synonym: corpus luteum hormone unit, unit of luteinizing activity. (05 Mar 2000) |
| progesterone-11HS-horseradish peroxidase | <chemical> Used as a tracer in an immunoassay for progesterone Synonym: p-11hs-hrp, progesterone-11hs-hrp (26 Jun 1999) |
| progesterone-3-(O-carboxymethyl oxime)-horseradish peroxidase | <chemical> Used as a tracer in an immunoassay for progesterone Synonym: progesterone-3-(o-carboxymethyl oxime)-hrp, p-3cmo-hrp (26 Jun 1999) |
| progesterone-6-hydroxylase | <enzyme> Cytochrome p-450 2c3 with valine at position 364 which confers 6beta-hydroxylase activity; see also record for cyp2c3 gene product Registry number: EC 1.14.99.- Synonym: progesterone 6beta-hydroxylase, cytochrome p450 2c3v (26 Jun 1999) |
| progesterone-binding globulin | A glycoprotein migrating as alpha 1-globulin, molecular weight 70,000 to 120,000. The protein, which is present in increased amounts in the plasma during pregnancy, binds mainly progesterone, with other steroids including testosterone competing weakly. (12 Dec 1998) |