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procyclidine hydrochloride [USP] a synthetic anticholinergic with a direct antispasmodic effect on smooth muscle; used as an antidyskinetic in the treatment of parkinsonism and for the control of drug-induced extrapyramidal reactions (except tardive dyskinesia), administered orally. It is believed to act by partially blocking central cholinergic receptors, which helps balance cholinergic and dopaminergic activity in the basal ganglia.
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