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amide synthases <enzyme> Enzymes that catalyze the joining of either ammonia or an amide with another molecule, in which the linkage is in the form of a carbon-nitrogen bond.
Registry number: EC 6.3.1
(12 Dec 1998)
peptide synthases <enzyme> Enzymes that catalyze the joining of an acid and an amino acid by the formation of a carbon-nitrogen bond.
Registry number: EC 6.3.2.
(12 Dec 1998)
polyketide beta-ketoacylsynthase <enzyme> A component of polyketide synthase complex; mapped by analogy with fatty acid synthetase complex.
Registry number: EC 2.3.1.-
Synonym: pks beta-ketoacyl synthase, acti gene product, actinorhodin polyketide synthase
(26 Jun 1999)
polyketide synthase <chemical> A group of enzymes functionally and structurally resembling the fatty acid synthase complex of microorganisms which produce the benzoisochromane quinone moiety of granaticin and other antibiotic; genbank y10438 (fkba)
Chemical name: synthetase, polyketide
Synonym: 6-deoxyerythronolide b synthase, 6-deoxyerythronolide-b synthase, debs, type II polyketide beta-ketoacyl synthase, griseusin polyketide synthase, type I polyketide synthase, sterigmatocystin polyketide synthase, st polyketide synthase, urdamycin polyketide synthase, polyketide synthase l1, pksl1 gene product, fkba gene product, niddamycin polyketide synthase, pks enzyme
(26 Jun 1999)
polyketide synthase ketoreductase <enzyme> A component of the polyketide synthase; mapped by analogy with fatty acid synthetase complex.
Registry number: EC 1.1.-
Synonym: pks ketoreductase, actiii gene product
(26 Jun 1999)
daunorubicin-doxorubicin polyketide synthase <chemical> Required for doxorubicin biosynthesis; involved in the selection of propionyl-CoA as the starter unit to the formation of a decaketide and its cyclization to an aklanonic acid to the formation of doxorubicin; genbank l35560
Synonym: dnr-dxr pks, doxorubicin polyketide synthase, dxr pks, dps gene product
(26 Jun 1999)
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