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acid phosphatase <enzyme> An enzyme that catalyses the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate.
Chemical name: Orthophosphoric-monoester phosphohydrolase (acid optimum)
Registry number: EC 3.1.3.2
(12 Dec 1998)
acid phosphatase test for semen A screening test for semen by determining acid phosphatase content; because seminal fluid contains high concentrations of acid phosphatase, while other body fluids and extraneous foreign materials have very low concentrations, high values of acid phosphatase on vaginal aspirate or lavage, or on wash fluid from stains, render positive identification of semen, even if the male is aspermic.
(05 Mar 2000)
Gomori's non-specific acid phosphatase stain <technique> A method in which formalin-fixed frozen sections are incubated in a substrate containing sodium beta-glycerophosphate and lead nitrate at pH 5.0; the insoluble lead phosphate produced is treated with ammonium sulfide to give a black lead sulfide.
(05 Mar 2000)
prostate acid phosphatase An enzyme produced by the prostate that is elevated in some patients with prostate cancer.
(12 Dec 1998)
purple acid phosphatase <enzyme> 110-kD glycoprotein with fe(iii)-zn(ii) centre; isolated from the red kidney bean phaseolus vulgaris; genbank p80366
Registry number: EC 3.1.3.-
Synonym: tartrate-resistant purple acid phosphatase, fe(iii)-zn(ii) purple acid phosphatase, kbpase
(26 Jun 1999)
okadaic acid-sensitive phosphatase <enzyme> Negatively controls the cyclin degradation pathway in amphibian eggs
Registry number: EC 3.1.3.-
Synonym: oas-phosphatase
(26 Jun 1999)
tartrate-resistant acid phosphatase <biochemistry, enzyme> Acid phosphatase is present in bone, prostate, platelets, erythrocytes and spleen.
Osteoclasts contain an isoenzyme that is resistant to tartrate, whereas, the isoenzyme in the prostate is sensitive. Tartrate-resistant acid phosphatase is elevated in the serum of patients with primary hypoparathyroidism, Paget disease, vertebral osteoporosis, T-cell lymphoma and in women after oophorectomy. Oestrogen replacement in osteoporotic postmenopausal women is associated with a decrease in tartrate-resistant acid phosphatase of 70% over 3 to 6 months.
Acronym: TRAP
(16 Dec 1997)
lysophosphatidic acid phosphatase <enzyme> Forms 1-acyl-sn-glycerol plus pi
Registry number: EC 3.1.3.-
(26 Jun 1999)
acetyl CoA carboxylase phosphatase <enzyme> Phosphatase occurs in complex with the carboxylase
Registry number: EC 3.1.3.-
Synonym: acc-phosphatase, acetyl coenzyme a carboxylase phosphatase
(26 Jun 1999)
alkaline phosphatase <enzyme> An enzyme that catalyses the cleavage of inorganic phosphate non-specifically from a wide variety of phosphate esters and having a high (greater than 8) pH optimum. Found in bacteria, fungi and animals but not in higher plants.
(18 Nov 1997)
PAC1 phosphatase <enzyme> An immediate-early mitogen-inducible tyrosine phosphatase; a map kinase phosphatase; amino acid sequence has been determined
Registry number: EC 3.1.3.-
Synonym: pac-1
(26 Jun 1999)
galactose-1-phosphatase <enzyme> From rat brain; requires mg for activity; phosphate is potent inhibitor
Registry number: EC 3.1.3.-
(26 Jun 1999)
CD45 phosphatase <enzyme> Reverses glycoprotein cd3-induced microtubule-associated protein-2 kinase activity in jurkat t-cells
Registry number: EC 3.1.3.-
Synonym: glycoprotein-cd45 phosphatase, cd45 ptpase, cd45 phosphotyrosine phosphatase
(26 Jun 1999)
glucose-1-phosphatase <enzyme> Catalyses the conversion of d-glucose 1-phosphate and water to d-glucose and orthophosphate
Registry number: EC 3.1.3.10
Synonym: agp gene product
(26 Jun 1999)
glucose-3-phosphatase <enzyme> From rat liver; has glucose-3-phosphate hydrolytic activity
Registry number: EC 3.1.3.-
(26 Jun 1999)
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