| Palmer acid test for peptic ulcer | In duodenal ulcer, the administration of acid by duodenal tube causes severe pain. (05 Mar 2000) |
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| peptic ulcer | <gastroenterology> An ulcer in the wall of the stomach or duodenum resulting from the digestive action of the gastric juice on the mucous membrane when the latter is rendered susceptible to its action. (13 Nov 1997) |
| peptic ulcer perforation | Penetration of a peptic ulcer through the stomach wall. May be free, i.e., at a point where the stomach wall faces a real or potential space,, or confined, i.e., at a point where the stomach wall is defended by contiguous or adjacent structures, such as the pancreas. (12 Dec 1998) |
| ulcer, peptic | A peptic ulcer is a hole in the lining of the stomach, duodenum, or oesophagus. A peptic ulcer of the stomach is called a gastric ulcer, an ulcer of the duodenum is a duodenal ulcer, and a peptic ulcer of the oesophagus is an oesophageal ulcer. A peptic ulcer occurs when the lining of these organs is corroded by the acidic digestive juices which are secreted by the stomach cells. Peptic ulcer disease is common, affecting millions of americans yearly. The medical cost of treating peptic ulcer and its complications runs in the billions of dollars annually in the u.s. Recent medical advances have increased our understanding of ulcer formation. Improved and expanded treatment options are now available. (12 Dec 1998) |
| peptic | Pertaining to pepsin or to digestion, related to the action of gastric juices. Origin: Gr. Peptikos (18 Nov 1997) |
| peptic cell | <pathology> Cells of the basal part of the gastric glands of the stomach. They contain extensive rough endoplasmic reticulum and zymogen granules and secrete pepsinogen, the inactive precursor of pepsin and rennin. (18 Nov 1997) |
| peptic digestion | That part of digestion, chiefly of the proteins, carried on in the stomach by the enzymes of the gastric juice. Synonym: peptic digestion. (05 Mar 2000) |
| peptic gland | A pepsin-secreting gland. See: gastric glands. (05 Mar 2000) |
| oesophagitis, peptic | Inflammation of the oesophagus caused by reflux of gastric juice and/or stomach and duodenal contents. (12 Dec 1998) |
| acceptor site | The ribosomal binding site for the aminoacyl-tRNA during protein synthesis. (05 Mar 2000) |
| acceptor splicing site | Boundary between the right end of an intron and the left end of the adjacent exon. Synonym: acceptor splicing site. (05 Mar 2000) |
| active site | <chemistry> A specific region of an enzyme where a substrate binds and catalysis takes place (binding site). (06 May 1997) |
| allosteric site | A specific site on a multi-subunit enzyme or other protein that is not the substrate binding site, but that when reversibly bound by an effector, induces a conformational change in the protein, altering its catalytic or binding properties. (12 Dec 1998) |
| amidation site | <molecular biology> A C terminus consensus sequence, required for C terminus amidation of peptides. Consensus is glycine, followed by 2 basic amino acids (arg or lys). (18 Nov 1997) |
| antibody combining site | <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope). Also used of the site on a ligand molecule to which a cell surface receptor binds. (18 Nov 1997) |