| PRPP | <abbreviation> 5-phospho-alpha-d-ribosyl 1-pyrophosphate. (05 Mar 2000) |
|---|---|
| PRPP synthetase | <enzyme> An enzyme that catalyses the reaction of alpha-d-ribose-5-phosphate and ATP to produce PRPP and AMP; a regulatory enzyme in purine and pyrimidine biosynthesis; enhanced activity of this enzyme results in an increase in purine biosynthesis leading to gout. (05 Mar 2000) |