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PROC A vitamin K-dependent protein in plasma that enters into the cascade of biochemical events leading to the formation of a clot.
(12 Dec 1998)
procainamide <chemical> A derivative of procaine with less CNS action. It is used in cardiac arrhythmias.
It differs chemically from procaine by containing the amide group (CONH) instead of the ester group (COO). It depresses the irritability of the cardiac muscle, having a quinidine-like action upon the heart, and is used in ventricular arrhythmias.
Pharmacological action: anti-arrhythmia agents, platelet aggregation inhibitors. Suppresses ventricular ectopy by slowing Phase 4 diastolic depolarisation, reducing automaticity. Slows conduction and may prevent reentrant rhythms.
Uses: Treat premature ventricular contractions and ventricular tachycardia. May convert supraventricular arrhythmias.
Dose: IV Loading: 20-30 mg/min until toxicity or desired effect up to 17 mg/kg Maintenance: 1-4 mg/min infusion Reduce dosage if heart or renal failure.
Potential complications: QRS widening and PR prolongation on the ECG. AV Block or asystole may follow. Rapid administration causes hypotension from vasodilation.
Chemical name: 4-amino-N-(2-(diethylamino)ethyl)-benzamide
(12 Mar 2000)
procainamide hydrochloride (05 Mar 2000)
procaine <drug> Organic base (234 D). Procaine butyrate, borate and hydrochloride are used as local anaesthetics.
(18 Nov 1997)
procaine esterase <enzyme> Aspect of EC 3.1.1.1,carboxylesterase
Registry number: EC 3.1.1.-
(26 Jun 1999)
procaine hydrochloride 2-Diethylaminoethyl p-aminobenzoate monohydrochloride;a local anaesthetic for infiltration and spinal anaesthesia; previously widely used but now infrequently employed.
(05 Mar 2000)
procambium <plant biology> Plant meristem that gives rise to the primary vascular system.
(18 Nov 1997)
procapsid A protein shell lacking a virus genome.
(05 Mar 2000)
procarbazine <chemical> N-(1-methylethyl)-4-((2-methylhydrazino)methyl)benzamide. An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the mopp protocol) in the treatment of hodgkin's disease. It is unrelated to other antineoplastic agent and may therefore be effective when other agents have failed.
Pharmacological action: antineoplastic agent, carcinogens.
Chemical name: Benzamide, N-(1-methylethyl)-4-((2-methylhydrazino)methyl)-
(12 Dec 1998)
procarbazine hydrochloride Ibenzmethyzin hydrochloride; N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide monohydrochloride;an antineoplastic agent.
(05 Mar 2000)
procarboxypeptidase Inactive precursor of a carboxypeptidase.
(05 Mar 2000)
procarcinogens Inactive xenobiotics that are converted to carcinogens in the organism.
(05 Mar 2000)
procardia <drug> A calcium channel blocker (346 D) used experimentally and as a coronary vasodilator.
(18 Nov 1997)
Procaryotae Synonym: Prokaryotae.
Origin: pro-+ G. Karyon, kernel, nut
(05 Mar 2000)
procaryote Organisms, namely bacteria and cyanobacteria (formerly known as blue green algae), characterised by the possession of a simple naked DNA chromosome, occasionally two such chromosomes, usually of circular structure, without a nuclear membrane and possessing a very small range of organelles, generally only a plasma membrane and ribosomes.
(18 Nov 1997)
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