| pepsic | Pertaining to pepsin or to digestion, related to the action of gastric juices. Origin: Gr. Peptikos (18 Nov 1997) |
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| pepsin | <protein> Acid protease from stomach of vertebrates. Cleaves preferentially between two hydrophobic amino acids (e.g. F L, F Y) and will attack most proteins except protamines, keratin and highly glycosylated proteins. A single chain phosphoprotein (327 amino acids, 34.5 kD) released from the enzymatically inactive zymogen, pepsinogen, by autocatalysis at acid pH in the presence of HCl. One of the peptides cleaved off in this process is a pepsin inhibitor and has to be further degraded to allow the pepsin to have full activity. (18 Nov 1997) |
| pepsin a | <enzyme> Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice. Pharmacological action: gastrointestinal agents. Registry number: EC 3.4.23.1 (12 Dec 1998) |
| pepsinate | To mix pepsin with. (05 Mar 2000) |
| pepsinhydrochloric | <physiology> Same as Peptohydrochloric. Source: Websters Dictionary (01 Mar 1998) |
| pepsiniferous | Producing pepsin. Synonym: pepsiniferous. (05 Mar 2000) |
| pepsinogen | The inactive precursor (42.5 kD) of pepsin. (18 Nov 1997) |
| pepsinogenous | Producing pepsin. Synonym: pepsiniferous. (05 Mar 2000) |
| pepsinuria | Excretion of pepsin in the urine. Origin: pepsin + G. Ouron, urine (05 Mar 2000) |
| pepstatin | An inhibitor peptide from actinomycetes that inhibits pepsin and cathepsin D. (05 Mar 2000) |
| pepstatins | <chemical> N-acylated oligopeptides isolated from culture filtrates of actinomycetes, which act specifically to inhibit acid proteases such as pepsin and renin. Pharmacological action: protease inhibitors. (12 Dec 1998) |