| opianic | <chemistry> Of, pertaining to, or designating, an organic acid obtained by the oxidation of narcotine. Origin: From Opium. Source: Websters Dictionary (01 Mar 1998) |
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| opianine | <chemistry> An alkaloid found in small quantity in opium. It is identical with narcotine. Source: Websters Dictionary (01 Mar 1998) |
| opianyl | <chemistry> Same as Meconin. Origin: Opianic + -yl. Source: Websters Dictionary (01 Mar 1998) |
| opiate | <pharmacology> A remedy containing or derived from opium, also any drug that induces sleep. Naturally occuring basic (alkaloid) molecules with a complex fused ring structure. Have high pharmacological activity. See: morphine. (18 Nov 1997) |
| opiate receptor | <pharmacology> Opiate-binding sites found throughout primary afferents and the neuraxis. (16 Dec 1997) |
| opiate receptors | Regions of the brain which have the capacity to bind morphine; some, along the aqueduct of Sylvius and in the centre median, are in areas related to pain, but others, as in the striatum, are not related. (05 Mar 2000) |
| opine | <molecular biology> Compound produced by plant cells containing T DNA: induce transfer genes on Ti plasmids. (18 Nov 1997) |
| opioid | Originally, a term denoting synthetic narcotics resembling opiates but increasingly used to refer to both opiates and synthetic narcotics. (05 Mar 2000) |
| opioid agonist | <pharmacology> Any morphine-like compound that produces bodily effects including pain relief, sedation, constipation and respiratory depression. (16 Dec 1997) |
| opioid antagonists | Agents such as naloxone and naltrexone which have high affinity for opiate receptors but do not activate these receptors. These drugs block the effects of exogenously administered opioids such as morphine, heroin, meperidine, and methadone, or of endogenously released endorphins and enkephalins. (05 Mar 2000) |
| opioid partial agonist | <pharmacology> A compound that has an affinity for and stimulates physiologic activity at the same cell receptors as opioid agonists but that produces only a partial (i.e., submaximal) bodily response. (16 Dec 1997) |
| opioid peptides | The endogenous peptides with opiate-like activity. The three major classes currently recognised are the enkephalins, the dynorphins, and the endorphins. Each of these families derives from different precursors, proenkephalin, prodynorphin, and pro-opiomelanocortin, respectively. There are also at least three classes of opioid receptors, but the peptide families do not map to the receptors in a simple way. (12 Dec 1998) |
| opioid receptor | <pharmacology> A membrane protein, widely distributed in animal cells, but especially in the brain (enkephalin receptors) and gut. The natural ligands are the opiate peptide neurotransmitters, but the name is given because opiates are potent agonists that occupy the receptors and mimic the action of the natural transmitters. (18 Nov 1997) |
| opioid-related disorders | Disorders related or resulting from abuse or mis-use of opioids. (12 Dec 1998) |
| opiomelanocortin | A linear polypeptide of the pituitary gland that contains in its sequence the sequences of endorphins, MSH, ACTH, and the like, which are split off enzymically; the nucleotide sequences coding has been determined for several species. (05 Mar 2000) |