| Nissl | Franz, German neurologist, 1860-1919. See: Nissl bodies, Nissl degeneration, Nissl granules, Nissl substance, Nissl's stain. (05 Mar 2000) |
|---|---|
| nissl bodies | Large granular basophilic bodies found in the cytoplasm of neurons, composed of rough endoplasmic reticulum and free polyribosomes. (12 Dec 1998) |
| Nissl degeneration | Degeneration of the cell body occurring after transection of the axon; characterised by dispersion of the granular endoplasmic reticulum, swelling of the soma, and an eccentric position of the nucleus of the cell. (05 Mar 2000) |
| Nissl granule | <cell biology> Discrete clumps of material seen by phase contrast microscopy in the perikaryon of some neurons, particularly motor neurons. They are basophilic and contain much RNA, are actually regions very rich in rough endoplasmic reticulum. Their reaction following damage to neurons is characteristic, they disperse through the cytoplasm giving a general basophilia to the whole cell body. (18 Nov 1997) |
| Nissl granules | The material consisting of granular endoplasmic reticulum and ribosomes that occurs in nerve cell bodies and dendrites. Synonym: basophil substance, basophilic substance, chromophil substance, Nissl bodies, Nissl granules, substantia basophilia, tigroid bodies, tigroid substance. (05 Mar 2000) |
| Nissl substance | The material consisting of granular endoplasmic reticulum and ribosomes that occurs in nerve cell bodies and dendrites. Synonym: basophil substance, basophilic substance, chromophil substance, Nissl bodies, Nissl granules, substantia basophilia, tigroid bodies, tigroid substance. (05 Mar 2000) |
| Nissl's stain | <technique> A method for staining nerve cells with basic fuchsin, a method for staining aggregates of rough endoplasmic reticulum and ribosomes in neuronal cell bodies and dendrites with basic dyes such as cresyl violet (or cresyl echt violet), thionine, toluidin blue O, or methylene blue. (05 Mar 2000) |