| 영문 | neurofibromatosis | 한글 | 신경섬유종증 |
|---|---|---|---|
| 설명 | 전신의 여러곳에 무더기로 나는 신경섬유종을 특징으로 하는 유전성 전신 병. 말초 신경뿐 아니라 중추 신경계도 침범할 수 있다. 신경섬유종은 주로 전신의 피부에 발생되지만 신경얼기 혹은 내장에 생기는 수도 있다. 피부에는 또한 곳곳에 특유의 갈색색소반을 보게 된다. 골격의 변형을 일으킬 수도 있다. 신경초종이나 악성신경초종, 더욱이 신경교종이나 수막종 등의 두개내종양을 합병함도 알려져 있다. 1형(von Recklinghausen 병, 전형적 신경섬유종증)과 2형(중추형 또는 청각신경섬유종증)으로 구분한다. 전형적 신경섬유종증(1형)이 가장 많이 발생하며 다음과 같은 3가지 소견을 보인댜. 즉 ① 체표면, 체내 여러 곳에 산재되어 발생하는 얼기모양신경종, ② 우유커피반점, ③ 리쉬(Lisch) 결절로 불리는 홍채의 착색과오종이다. 2형은 1형보다 발생빈도가 적고, 특징적으로 양쪽성 청각신경종이 있으며, 우유반점은 보이나 리쉬결절은 없다. |
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| ECG | Electro-Cardio-Graphy(-Gram); 심전도 = EKG 1. Conducting System Structu... |
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| PMD | Progressive Muscular Dystrophy; 진행성 근이영양증 Types of PMD(Progressive Muscular Dystroph... |
| TAPVR | Total Anomalous Pulmonary Venous Return = TAPVC 4 Types of TAPVR &... |
| NF1 | neurofibromatosis type I; nuclear factor 1 |
| NF2 | neurofibromatosis type II |
| NF1 | NEUROFIBROMATOSIS TYPE 1 |
|---|---|
| NF2 | Neurofibromatosis Type 2 |
| NF I | Neurofibromatosis type I |
| NF | Neurofibromatosis |
| NF 1 | Neurofibromatosis |
| central type neurofibromatosis | Type I neurofibromatosis. Incomplete neurofibromatosis, multiple neurofibromas with minimal manifestations, perhaps limited to cafe-au-lait spots; individuals with minimal lesions may have offspring with severe involvement. Synonym: abortive neurofibromatosis. (05 Mar 2000) |
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| abortive neurofibromatosis | incomplete neurofibromatosis |
| genes, neurofibromatosis 1 | Tumour suppressor genes located on the long arm of human chromosome 17 in the region 17q11.2. Mutation of these genes is thought to cause neurofibromatosis 1. (12 Dec 1998) |
| genes, neurofibromatosis 2 | Tumour suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes neurofibromatosis 2. (12 Dec 1998) |
| neurofibromatosis | <oncology> One of the most common disorders in genetics, neurofibromatosis encompasses at least two diseases, designated NF-1 and NF-2. NF-1 or classic neurofibromatosis, is characterised by the familiar cafe- au-lait spots, axillary freckling, cutaneous and visceral neurofibromas (which sometimes undergo malignant transformation), gliomas, scoliosis, and Lisch nodules of the iris. NF-1 is associated with the the von Recklinghausen Neurofibromatosis locus that encodes the NF-1 protein, a GTPase activating protein which interacts with the ras proteins. The gene is located on chromosome 17. NF-2, also called acoustic or central neurofibromatosis, features neurofibromas restricted to the acoustic nerve (usually bilateral) and the central nervous system, skin lesions may or may not be present. The gene is located on chromosome 22. There are no biochemical markers of the disorder, but the cloning of both the NF-1 and NF-2 genes makes DNA-based diagnosis possible in some families. Both genes appear to be tumour suppressor genes. Both conditions are autosomal dominant, but the variable penetrance and expressivity and high frequency of new mutations make genetic counseling difficult. Inheritance: autosomal dominant. (29 Dec 1997) |
| neurofibromatosis 1 | A congenital autosomal dominant disorder characterised by developmental changes in the nervous system, muscles, bones, and skin especially in those derived from the embryonic neural crest. There are multiple cutaneous tumours and tumours of the peripheral and central nervous system. The disease has been linked to mutations of the nf1 gene on chromosome 17. (12 Dec 1998) |
| neurofibromatosis 2 | Severe autosomal dominant disorder characterised especially by bilateral acoustic neuromas as well as other multiple tumours including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the nf2 gene on chromosome 22. (12 Dec 1998) |
| acrocephalosyndactyly type 1 | <paediatrics> An inherited disease (autosomal dominant) or a spontaneously occurring disease characterised by a peaked head and unusual facial appearance, due to the premature closure of the cranial sutures. A skull X-ray can confirm the diagnosis and treatment is surgical. Inheritance: autosomal dominant. (27 Sep 1997) |
| Alzheimer type I astrocyte | Enlarged frequently multinucleated astrocytes, seen in progressive multifocal leukoencephalopathy. (05 Mar 2000) |
| Alzheimer type II astrocyte | Enlarged astrocytes with vesicular nuclei and one or more small basophilic nucleoli, seen in hepatocerebral disease and Wilson's disease. (05 Mar 2000) |
| American Type Culture Collection | <cell culture> A key resource for cultured cells, located in Rockville, USA. (12 Dec 1998) |
| Antoni type A neurilemoma | <tumour> Relatively solid or compact arrangement of neoplastic tissue that consists of Schwann cells arranged in twisting bundles and associated with delicate reticulin fibres; the nuclei of the Schwann cells are frequently grouped in parallel rows (so-called palisades), and the nuclei and fibres sometimes form exaggerated tactile corpuscles, called Verocay bodies. (05 Mar 2000) |
| Antoni type B neurilemoma | <tumour> Relatively soft or loose arrangement of neoplastic tissue that consists of Schwann cells in a haphazard or nondescript type of arrangement among reticulin fibres and tiny cystlike foci; fat-laden macrophages may be observed in some of the larger neoplasms. (05 Mar 2000) |
| arthus-type reaction's | Reaction's in man and other species that result from the same basic immunologic (allergic) mechanism which evokes, in the rabbit, the typical Arthus phenomenon. See: immune complex disease. (05 Mar 2000) |
| avian adenovirus type 1 proteinase | <enzyme> 206 aa residues of which 66% are homologous to human ad2 emzyme embl/genbank l13161 Registry number: EC 3.4.22.- Synonym: aavl proteinase, aavl endopeptidase (26 Jun 1999) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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