Neuroblastoma : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

CancerWEB 영영 의학사전 맞춤 검색 결과 : 1 페이지: 1

neuroblastoma	<oncology, tumour> Malignant tumour derived from primitive ganglion cells. Mainly a tumour of childhood. Commonest sites are adrenal medulla and retroperitoneal tissue. The cells may partially differentiate into cells having the appearance of immature neurons. The tumour shows a consistent deletion of the 1p36 region which is considered the site of the neuroblastoma I gene. Loss of the 1p36 region also correlates with amplification for the N-myc oncogene, particularly in later stages of the disease. Amplification of N-myc with DNA triploidy is associated with poor survival. Hereditary forms of the condition are rare and in such patients there is no risk for other cancers, which suggests a specificity of the antioncogene for neural tissues. (16 Dec 1997)

neuroblastoma

<oncology, tumour> Malignant tumour derived from primitive ganglion cells. Mainly a tumour of childhood. Commonest sites are adrenal medulla and retroperitoneal tissue. The cells may partially differentiate into cells having the appearance of immature neurons.
The tumour shows a consistent deletion of the 1p36 region which is considered the site of the neuroblastoma I gene. Loss of the 1p36 region also correlates with amplification for the N-myc oncogene, particularly in later stages of the disease.
Amplification of N-myc with DNA triploidy is associated with poor survival.
Hereditary forms of the condition are rare and in such patients there is no risk for other cancers, which suggests a specificity of the antioncogene for neural tissues.
(16 Dec 1997)