Neural Cell Adhesion Molecule L1 : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 1 페이지: 1

Neural Cell Adhesion Molecule L1 - 새창 A member of the immunoglobulin superfamily of neuronal cell adhesion molecules that is required for proper nervous system development. Neural cell adhesion molecule L1 consists of six Ig domains, five fibronectin domains, a transmembrane region and an intracellular domain. Two splicing variants are known: a neuronal form that contains a four-amino acid RSLE sequence in the cytoplasmic domain, and a non-neuronal form that lacks the RSLE sequence. Mutations in the L1 gene result in L1 disease. Neural cell adhesion molecule L1 is predominantly expressed during development in neurons and Schwann cells; involved in cell adhesion, neuronal migration, axonal growth and pathfinding, and myelination.
Synonyms : CALL Protein, CamL1 Gene Product, Cell Adhesion Molecule L1, Cell Surface Glycoprotein L1, F11 Glycoprotein, L1 Cell Adhesion Molecule, L1CAM, NGF-Inducible Glycoprotein, NILE Glycoprotein, NILE Protein, Nerve Growth Factor-Inducible Large External Glycoprotein