NFATC Transcription Factors : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 1 페이지: 1

NFATC Transcription Factors - 새창 A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.
Synonyms : NF-AT Proteins, NF-AT3 Protein, NF-AT4 Protein, NF-ATc1 Protein, NFAT Proteins, NFAT-1 Protein, NFAT-2 Protein, NFAT1 Protein, NFAT2 Protein, NFAT3 Protein, NFAT4 Protein, NFAT5 Protein, NFATC Proteins, NFATC1 Protein, NFATC1 Transcription Factor, NFATC2 Protein