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nalbuphine <chemical> A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors.
Pharmacological action: analgesics, opioid, narcotic antagonists, narcotics.
Chemical name: Morphinan-3,6,14-triol, 17-(cyclobutylmethyl)-4,5-epoxy-, (5alpha,6alpha)-
(12 Dec 1998)
nalbuphine hydrochloride 17-(Cyclobutylmethyl)4,5a-epoxymorphinan-3,6a,14-triol hydrochloride;a synthetic opioid analgesic chemically related to oxymorphone, a narcotic, and to naloxone, a narcotic antagonist, with both agonist and antagonist narcotic properties.
(05 Mar 2000)
naled <chemical> An organophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
Pharmacological action: cholinesterase inhibitor, insecticide, organophosphate.
Chemical name: Phosphoric acid, 1,2-dibromo-2,2-dichloroethyl dimethyl ester
(12 Dec 1998)
nalidixic acid <drug> Synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication. Often used in selective media.
(18 Nov 1997)
nalorphine <chemical> (5 alpha,6 alpha)-7,8-didehydro-4,5-epoxy-17-(2-propenyl)morphinan-3,6-diol. A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.
Pharmacological action: narcotic antagonists.
Chemical name: Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5alpha,6alpha)-
(12 Dec 1998)
naloxone <drug> An alkaloid antagonist of morphine and of the opiate peptides.
(18 Nov 1997)
naloxone hydrochloride 1-N-Allyl-7,8-dihydro-14-hydroxymorphinone hydrochloride;a potent antagonist of endorphins and narcotics, including pentazocine; devoid of pharmacologic action when administered without narcotics.
(05 Mar 2000)
naltrexone <chemical> Derivative of noroxymorphone that is the n-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Pharmacological action: narcotic antagonists.
Chemical name: Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5alpha)-
(12 Dec 1998)
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