| NADH, NADPH oxidoreductases | <enzyme> A group of oxidoreductases that act on NADH or NADPH. In general, enzymes using NADH or NADPH to reduce a substrate are classified according to the reverse reaction, in which NAD+ or NADP+ is formally regarded as an acceptor. This subclass includes only those enzymes in which some other redox carrier is the acceptor. Registry number: EC 1.6. (12 Dec 1998) |
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| alcohol oxidoreductases | <enzyme> A subclass of enzymes which includes all dehydrogenases acting on primary and secondary alcohols as well as hemiacetals. They are further classified according to the acceptor which can be NAD+ or NADP+ (subclass 1.1.1), cytochrome (1.1.2), oxygen (1.1.3), quinone (1.1.5), or another acceptor (1.1.99). Registry number: EC 1.1 (12 Dec 1998) |
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| aldehyde oxidoreductases | <enzyme> Registry number: EC 1.2. (12 Dec 1998) |
| amine oxidoreductases | <enzyme> Enzymes catalyzing the dehydrogenation of secondary amines, introducing a c=n double bond as the primary reaction. In some cases this is later hydrolyzed. Registry number: EC 1.5. (12 Dec 1998) |
| amino acid oxidoreductases | <enzyme> A class of enzymes that catalyze oxidation-reduction reactions of amino acids. Registry number: EC 1.4. (12 Dec 1998) |
| intramolecular oxidoreductases | <enzyme> Enzymes of the isomerase class that catalyze the oxidation of one part of a molecule with a corresponding reduction of another part of the same molecule. They include enzymes converting aldoses to ketoses (aldose-ketose isomerases), enzymes shifting a carbon-carbon double bond (carbon-carbon double bond isomerases), and enzymes transposing s-s bonds (sulfur-sulfur bond isomerases). Registry number: EC 5.3 (12 Dec 1998) |
| oxidoreductases | <enzyme> The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidised is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where o2 is the acceptor. (enzyme nomenclature, 1992, p9) Registry number: EC 1. (12 Dec 1998) |
| oxidoreductases, n-demethylating | <enzyme> Registry number: EC 1.5. (12 Dec 1998) |
| oxidoreductases, o-demethylating | <enzyme> Drug metabolizing enzymes which oxidise methyl ethers. Usually found in liver microsomes. Registry number: EC 1.- (12 Dec 1998) |
| ketone oxidoreductases | <enzyme> Registry number: EC 1.2. (12 Dec 1998) |
| acyl-CoA dehydrogenase (NADPH+) | Enzyme catalyzing the reversible reduction of enoyl-CoA derivatives of chain length 4 to 16, with NADPH as the hydrogen donor, forming acyl-CoA and NADP+. Synonym: enoyl-CoA reductase. (05 Mar 2000) |
| aromatic NADH-dependent nitroreductase | <enzyme> See also record for 1-nitroreductase; type I nitroreductase is not inhibited by oxygen Registry number: EC 1.- Synonym: nitrofuran reductase, nitrofurazone reductase, type I nitroreductases, NADH-dependent nitro reductase, nitrofurantoin reductase, p-dinitrobenzene reductase, benznidazole nitroreductase, nifurtimox nitroreductase, oxygen-insensitive NADPH nitroreductase, nitrobenzene nitroreductase (26 Jun 1999) |
| sodium-translocating NADH-quinone reductase | <enzyme> From vibrio alginolyticus; na+ dependent activation is located in the NADH-quinone reductase segment; reduces ubiquinone-1 to ubisemiquinones or ubiquinol; strongly inhibited by 2-n-heptyl-4-hydroxyquinoline n-oxide; do not confuse with sodium independent NADH-quinone reductase EC 1.6.99.2 Registry number: EC 1.6.5.- Synonym: nqr-1, na-translocating NADH-quinone reductase, nqr gene product (26 Jun 1999) |
| NADH | <abbreviation> Nicotinamide adenine dinucleotide (reduced form). (05 Mar 2000) |
| NADH-cytochrome P-450 reductase | <enzyme> A component of the cytochrome p-450sca monoxygenase system Registry number: EC 1.6.2.- (26 Jun 1999) |
| NADH dehydrogenase | <enzyme> A flavoprotein containing iron. Cytochrome c may act as receptor. The enzyme reversibly catalyses the oxidation of NADH to NAD and reduced acceptor. An inherited deficiency of this complex results in overwhelming acidosis. Synonym: cytochrome c reductase. Chemical name: NADH:(acceptor) oxidoreductase Registry number: EC 1.6.99.3 (12 Dec 1998) |