| myco- | Fungus. Origin: G. Mykes, fungus (05 Mar 2000) |
|---|---|
| mycobacillin | <chemical> A cyclic polypeptide antibiotic isolated from culture filtrates of bacillus subtilis that acts as an antifungal agent. Pharmacological action: antibiotics, antifungal, antibiotics, peptide. Chemical name: Mycobacillin (12 Dec 1998) |
| mycobacillin synthetase | <enzyme> Requires ATP and mg; is inhibited by sulfhydryl reagents Registry number: EC 6.3.2.- (26 Jun 1999) |
| mycobacteria | <microbiology> Bacteria with unusual cell walls that are resistant to digestion, being waxy, very hydrophobic and rich in lipid, especially esterified mycolic acids. Staining properties differ from those of gram-negative and gram-positive organisms, being acid-fast. Many are intracellular parasites, causing serious diseases such as leprosy and tuberculosis. Cell wall has strong immunostimulating (adjuvant) properties due to muramyl dipeptide (MDP). Mycobacterium bovis causes tuberculosis in cattle, attenuated strain is Bacille Calmette-Guerin (BCG), used for immunisation. Mycobacterium leprae is the causative agent of leprosy. Mycobacterium microti is a mycobacterium that causes tuberculosis like disease in small rodents (Microtus microtus is the vole), will infect mice but not humans and is therefore much used as a laboratory model. Releases large amounts of cAMP which may inhibit lysosome phagosome fusion. Mycobacterium tuberculosis Is an obligate anaerobic nonmotile bacterium, causative agent of tuberculosis in humans. Lives intracellularly in macrophages. (18 Nov 1997) |
| mycobacteriaceae | A family of gram-positive bacteria found in soil and dairy products and as parasites on animals and man. Several are important pathogens. (12 Dec 1998) |
| mycobacteriophages | Viruses whose host is one or more mycobacterium species. They include both temperate and virulent types. (12 Dec 1998) |
| mycobacteriosis | Infection with mycobacteria. (05 Mar 2000) |
| mycobacterium | <microbiology> An organism of the genus Mycobacterium. (18 Nov 1997) |
| Mycobacterium abscessus | A species originally found in a traumatic infection of the knee. Synonym: Mycobacterium abscessus. (05 Mar 2000) |
| mycobacterium avium | A bacterium causing tuberculosis in domestic fowl and other birds. In pigs, it may cause localised and sometimes disseminated disease. The organism occurs occasionally in sheep and cattle. It should be distinguished from the m. Avium complex, which infects primarily humans. (12 Dec 1998) |
| mycobacterium avium complex | A serious opportunistic infection caused by two similar bacteria (Mycobacterium avium and Mycobacterium intercellulare) found in the soil and dust particles. In AIDS, MAC can spread through the bloodstream to infect lymph nodes, bone marrow, liver, spleen, spinal fluid, lungs and intestinal tract. Typical symptoms of MAC include night sweats, weight loss, fever, fatigue, diarrhoea and enlarged spleen. MAC is usually found in people with CD4 counts below 100. MAC is also called MAI. (09 Oct 1997) |
| mycobacterium avium complex disease | <infectious disease> A disease process caused by infection by the organism Mycobacterium avium intracellulare. Almost unheard of in a patient with a normal functioning immune system, this can be a common infection in those with advanced HIV infection. (27 Sep 1997) |
| Mycobacterium avium-intracellulare complex | An opportunistic agent of people with AIDS. Difficult to treat because Mycobacterium is resistant to many antibiotics. May also cause chronic lower respiratory tract infections. (05 Mar 2000) |
| mycobacterium avium-intracellulare infection | Nontuberculous infection occurring in humans. This condition is frequently associated with pulmonary disease and recently recognised as an opportunistic infection in aids patients. (12 Dec 1998) |
| mycobacterium bovis | The bovine variety of the tubercle bacillus. It is called also mycobacterium tuberculosis var. Bovis. (12 Dec 1998) |