| malignant mixed mullerian tumour | A sarcoma of the body of the uterus arising in older women, composed of more than one mesenchymal tissue, especially including striated muscle cells. Synonym: malignant mixed mullerian tumour. (05 Mar 2000) |
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| mixed tumour, mullerian | A tumour, basically a carcinoma with a single sarcoma such as leiomyosarcoma or angiosarcoma or multiple sarcomas of uterine origin. The role of oestrogen has been postulated as a possible aetiological factor in this tumour. (holland et al., cancer medicine, 3d ed, p1703) (12 Dec 1998) |
| tumor | 1. <oncology> An abnormal mass of tissue that results from excessive cell division that is uncontrolled and progressive, also called a neoplasm. Tumours perform no useful body function. They may be either benign (not cancerous) or malignant. 2. Swelling, one of the cardinal signs of inflammations, morbid enlargement. Origin: L. Tumere = to swell (12 May 1997) |
| tumor marker | <investigation, oncology> A substance in the body that usually indicates the presence of cancer. These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples. Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH). They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids. (18 Jul 2002) |
| tumor necrosis factor | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |
| persistent mullerian duct syndrome | <syndrome> Familial disorder with presence of fallopian tube, uterus, and testis in a male. Deficient mullerian inhibitory substance secondary to Sertoli cell defect. Synonym: hernia uteri inguinale. (05 Mar 2000) |
| mullerian | <anatomy> Of, pertaining to, or discovered by, Johannes Muller. <anatomy> Mullerian ducts, the sustentacular or connective-tissue fibres which form the framework of the retina. Source: Websters Dictionary (01 Mar 1998) |
| mullerian adenosarcoma | <tumour> A tumour of the uterus or ovaries, of low grade malignancy, characterised by benign appearing glands and a sarcomatous stroma. (05 Mar 2000) |
| mullerian duct | <radiology> FEMALE, fallopian tubes, uterus, vagina Male, appendix testis, prostatic utricle anomalies: mullerian agenesis most likely to be absent uterus and vagina, incomplete fusion most likely to be bicornuate/double uterus, double vagina, both associated with renal agenesis Cf: wolffian duct (12 Dec 1998) |
| mullerian ducts | Two ducts of the embryo which empty into the cloaca, and which in the female develop into vagina, uterus and oviducts; in the male they disappear except for the vestigial vagina masculina and the appendix testis. (12 Dec 1998) |
| mullerian inhibiting factor | A 535 amino acid glycoprotein secreted by the Sertoli cells of the testis. It is related to inhibin. Synonym: mullerian inhibiting factor. (05 Mar 2000) |
| mullerian inhibiting substance | A 535 amino acid glycoprotein secreted by the Sertoli cells of the testis. It is related to inhibin. Synonym: mullerian inhibiting factor. (05 Mar 2000) |
| mullerian regression factor | Mullerian duct inhibitory factor, a non-steroidal substance of foetal testicular origin that acts unilaterally to inhibit development of the paramesonephric (mullerian) ducts and acts with testosterone to promote development of the vas deferens and related structures. (05 Mar 2000) |
| gonadal dysgenesis, mixed | A syndrome of gonadal dysgenesis in which there is a testis on one side and a "streak gonad" on the other. The phenotype is generally male, but may be female since the individual is a mosaic. Various karyotypes have been identified, including 45,xo/47,xyy; 45,xo/46,xy; and 45,xo/46,xyo. (12 Dec 1998) |
| mixed | Formed by mixing; united; mingled; blended. See Mix, Mixed action, voices of both males and females united in the same performance. Source: Websters Dictionary (01 Mar 1998) |