| RU-486 | mifepristone |
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| mifepristone | <chemical> A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing's syndrome. Pharmacological action: abortifacient agents, steroidal, contraceptives, oral, synthetic, contraceptives, postcoital, synthetic, hormone antagonists, luteolytic agents, menstruation-inducing agents. Chemical name: Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-, (11beta,17beta)- (12 Dec 1998) |
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Synonyms : Contragest Brand of Mifepristone, Danco Brand of Mifepristone, Exelgyn Brand of Mifepristone, Mifegyne, Mifeprex, Mifegyne, R-38486, R38486, RU-38486, RU-486, ZK-98296, ZK98296, Mifepristone Contragest Brand, Mifepristone Danco Brand, Mifepristone Exelgyn Brand
| mifepristone |
an antiprogestin used in combination with misoprostol or other prostaglandin as a postcoital contraceptive, terminating pregnancy in the first trimester; administered orally. Called also RU-486.
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| Mifepristone | an abortion-inducing drug (trade name Mifepristone) developed in France |
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