| metyrapone | <chemical> Chemical name: 1-Propanone, 2-methyl-1,2-di-3-pyridinyl- (12 Dec 1998) |
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| metyrapone reductase | <enzyme> From mouse liver microsomes, belongs to the family of carbonyl reductases; can use NADH or NADPH as co-substrates Registry number: EC 1.1.1.- (26 Jun 1999) |
| metyrapone test | <endocrinology, investigation> This test measures the ability of the pituitary gland to secrete ACTH in response to a low serum cortisol level. Under normal conditions a low serum cortisol level should stimulate the pituitary to produce ACTH, which stimulates the adrenal glands to produce more cortisol. This test is performed by injecting metyrapone into the bloodstream and then measuring cortisol levels over a period of time. Metyrapone is a substance which inhibits an enzyme (steroid 11-beta hydroxylase) involved in the synthesis of cortisol. This enzyme normally converts 11-deoxycortisol to cortisol. When the enzyme is inhibited, 11-deoxycortisol levels will increase in the blood and urine and cortisol levels will go down. This test is useful in differentiating the different forms of Cushing's syndrome: adrenal hyperplasia versus primary adrenal tumour. Those with an adrenal tumour (or carcinoma) generally have no response to metyrapone injection, since the dose is insufficient to inhibit cortisol synthesis. (27 Sep 1997) |
Synonyms : Alliance Brand of Metyrapone, Metopiron, Metopirone, Metopirone, Novartis Brand of Metyrapone, SU 4885, 4885, SU, Metyrapone Alliance Brand, Metyrapone Novartis Brand
| metyrapone |
[USP] an inhibitor of the enzyme steroid 11β-hydroxylase; used in a test of hypothalamic-pituitary function. See metyrapone test, under tests.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| metyrapone t. |
(for Cushing's syndrome): plasma 11-deoxycortisol or urinary 17-hydroxycorticosteroids are measured after the administration of metyrapone; levels are increased in patients with Cushing's disease but not in patients with ectopic ACTH syndrome.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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