| replica methods | <technique> Methods in the preparation of specimens for transmission electron microscopy. The specimen (for example: a piece of freeze fractured tissue) is shadowed with metal and coated with carbon and then the tissue is digested away. The replica is then picked up on a grid and it is the replica that is examined in the microscope. (18 Nov 1997) |
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| communication methods, total | Utilization of all available receptive and expressive modes for the purpose of achieving communication with the hearing impaired, such as gestures, postures, facial expression, types of voice, formal speech and non-speech systems, and simultaneous communication. (12 Dec 1998) |
| Crede's methods | Instillation of one drop of a 2% solution of silver nitrate into each eye of the newborn infant, to prevent ophthalmia neonatorum, resting the hand on the fundus uteri from the moment of the expulsion of the foetus, and gently rubbing in case of haemorrhage or failing contraction; then, when the afterbirth is loosened it is expelled by firm compression or squeezing of the fundus by the hand, use of manual pressure on a bladder, particularly a paralysed bladder, to express urine. Synonym: Crede's manoeuvres. (05 Mar 2000) |
| seroepidemiologic methods | Epidemiologic studies based on the detection through serological testing of characteristic change in the serum level of specific antibodies. Latent subclinical infections and carrier states can thus be detected in addition to clinically overt cases. (12 Dec 1998) |
| feeding methods | Methods of giving food to humans or animals. (12 Dec 1998) |
| relative molecular mass | The sum of the atomic weight's of all the atoms constituting a molecule; the mass of a molecule relative to the mass of a standard atom, now 12C (taken as 12.000). Relative molecular mass (Mr) is the mass relative to the dalton and has no units. See: atomic weight. Synonym: molecular mass, molecular weight ratio, relative molecular mass. (05 Mar 2000) |
| gram-molecular weight | Molecular weight expressed in grams. Compare: mole. (05 Mar 2000) |
| cloning, molecular | The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells. (12 Dec 1998) |
| models, molecular | Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures. (12 Dec 1998) |
| molecular | <chemistry> Of, pertaining to or composed of molecules: a very small mass of matter. (18 Nov 1997) |
| molecular behaviour | <psychology> Behaviour described in small response units rather than larger ones; a specific response. Compare: molar behaviour. (05 Mar 2000) |
| molecular biology | <study> The study of the biochemistry of cells, it is closely linked to cell biology, in particular the biochemistry of DNA and cogeners. (16 Dec 1997) |
| molecular biophysics | Biophysics concerned with membrane processes, conformational and configurational properties of macromolecules, bioelectrical phenomena, etc. (05 Mar 2000) |
| molecular chaperones | A family of cellular proteins that mediate the correct assembly or disassembly of other polypeptides, and in some cases their assembly into oligomeric structures, but which are not components of those final structures. It is believed that chaperone proteins assist polypeptides to self-assemble by inhibiting alternative assembly pathways that produce nonfunctional structures. Some classes of molecular chaperones are the nucleoplasmins, the chaperonins, the heat-shock proteins 70, and the heat-shock proteins 90. (12 Dec 1998) |
| molecular clock | This term has two separate uses. 1. <molecular biology> The rate of fixation of mutations in DNA and thus times the rate of genetic diversification. 2. <cell biology> A biological system capable of maintaining up a timing rhythm or pulse. All such clocks are thought to be entrained by a natural oscillator such as the diurnal rhythm. (18 Nov 1997) |