Metabolic Detoxication, Phase I : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 2 페이지: 1

Metabolic Detoxication, Phase I - 새창 Functionalization of exogenous substances to prepare them for conjugation in PHASE II DETOXIFICATION. Phase I enzymes include CYTOCHROME P450 enzymes and some OXIDOREDUCTASES. Excess induction of phase I over phase II detoxification leads to higher levels of FREE RADICALS that can induce CANCER and other cell damage. Induction or antagonism of phase I detoxication is the basis of a number of DRUG INTERACTIONS.
Synonyms : Metabolic Detoxication, Oxidative, Metabolic Detoxification, Phase I, Phase I Detoxification, Detoxication, Oxidative Metabolic, Detoxications, Oxidative Metabolic, Detoxification, Phase I, Detoxifications, Phase I, Metabolic Detoxications, Oxidative
Metabolic Detoxication, Phase II - 새창 Conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
Synonyms : Metabolic Detoxication, Conjugative, Metabolic Detoxification, Phase II, Phase II Detoxification, Conjugative Metabolic Detoxication, Conjugative Metabolic Detoxications, Detoxication, Conjugative Metabolic, Detoxications, Conjugative Metabolic