| Mesc | a colorless Mexican liquor distilled from fermented juices of certain desert plants of the genus Agavaceae (especially the century plant) |
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| Mesc | a small spineless globe-shaped cactus |
| Mesc | shrub or small tree having pinnate leaves poisonous to livestock and dense racemes of intensely fragrant blue flowers and red beans |
| Mesc | the button-shaped top of the mescal cactus |
| Mesc | the hallucinatory alkaloid that is the active agent in mescal buttons |