| mechlorethamine | <chemical> A vesicant and necrotizing irritant destructive to mucous membranes. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage. Pharmacological action: alkylating agents, antineoplastic agent, alkylating, chemical warfare agents, irritants. Chemical name: Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl- (12 Dec 1998) |
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| mechlorethamine hydrochloride | 2,2'-Dichloro-N-methyldiethylamine hydrochloride; methyl-bis(beta-chloroethyl)amine hydrochloride; nitrogen mustard hydrochloride;it is cytotoxic for all cells, but with a special affinity for bone marrow, lymphatic tissues, and rapidly proliferating cells of certain neoplasms. Used for the palliative treatment of Hodgkin's disease, lymphosarcoma, and certain chronic leukaemias. Synonym: mustine hydrochloride. (05 Mar 2000) |