| marfan syndrome | <radiology> Connective-tissue disorder: autosomal dominant, 15% sporadic, cardiovascular system (probable cause of death in 93%), aortic aneurysm (mostly ascending), dilatation of aortic sinuses, aortic dissection, coarctation, musculoskeletal system, tall stature, long limbs, arachnodactyly, lax joints, scoliosis (60%) / kyphosis / pectus, eye, lens subluxation Cf: homocystinuria More info: Marfan syndrome (12 Dec 1998) |
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| Marfan's disease | <syndrome> A hereditary condition of the connective tissue. Symptoms and signs include tall lean body type, irregular or unsteady gait, long extremities (including fingers and toes), abnormal joint flexibility, flat feet, stooped shoulders, dislocation of the optic lens and aneurysms of the aorta. Affects 1 in 50,000 people. Probably a collagen fibril assembly disorder since it can be mimicked in mice by aminonitriles that interfere with crosslinking. Inheritance: autosomal dominant. (06 Oct 1997) |
| Marfan's law | The healing of localised tuberculosis protects against subsequent development of pulmonary tuberculosis. (05 Mar 2000) |
| Marfan's syndrome | <syndrome> A hereditary condition of the connective tissue. Symptoms and signs include tall lean body type, irregular or unsteady gait, long extremities (including fingers and toes), abnormal joint flexibility, flat feet, stooped shoulders, dislocation of the optic lens and aneurysms of the aorta. Affects 1 in 50,000 people. Probably a collagen fibril assembly disorder since it can be mimicked in mice by aminonitriles that interfere with crosslinking. Inheritance: autosomal dominant. (06 Oct 1997) |
| Marfan, Antoine Bernard-Jean | <person> French paediatrician, 1858-1942. See: Marfan's disease, Marfan's law, Marfan's syndrome. (05 Mar 2000) |
| marfanoid | An obsolete term used of those whose phenotype bears a superficial resemblence to that of Marfan's syndrome. (05 Mar 2000) |
| syndrome, marfan | Inherited disorder with long fingers and toes, dislocation of the lens, and aortic wall weakness and aneurysm. (it has been suggested that abraham lincoln had marfan syndrome.) (12 Dec 1998) |
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