| Marek disease | <disease> Infectious cancer of the lymphoid system (lymphomatosis) in chickens, caused by a contagious Herpes virus. An effective vaccine is now available. (18 Nov 1997) |
|---|---|
| marek's disease | A lymphoproliferative disease of fowl caused by a herpes virus. Lymphoid cell infiltrations are most common in the peripheral nerves and gonads, but widespread infiltrations may also be found in any of the visceral organs, skin, muscle, and the iris of the eye. The location of the lesions dictates the clinical signs, such as paralysis, general depression, and blindness. (12 Dec 1998) |
| Marek's disease virus | The herpesvirus that causes avian lymphomatosis (Marek's disease); is distinct from those causing other forms of leukosis. Synonym: avian lymphomatosis virus, fowl neurolymphomatosis virus, Marek's disease virus. (05 Mar 2000) |
| Marek, Josef | <person> Hungarian veterinarian and pathologist, 1867-1952. See: Marek's disease, Marek's disease virus. (05 Mar 2000) |
| foot-and-mouth disease virus vaccines | Vaccine's either of inactivated virus from infected cattle tongue epithelium or, more recently, of live virus attenuated by embryonated egg or mouse passage and propagated in tissue culture. (05 Mar 2000) |
| aids vaccines | Vaccines or candidate vaccines containing inactivated HIV or some of its component antigens and designed to prevent aids. Some vaccines containing antigens are recombinantly produced. (12 Dec 1998) |
| bacterial vaccines | Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease. (12 Dec 1998) |
| cancer vaccines | Vaccines or candidate vaccines designed to prevent or treat cancer. Vaccines are produced using the patient's own whole tumour cells as the source of antigens, or using tumour-specific antigens, often recombinantly produced. (12 Dec 1998) |
| vaccines | Vaccines are microbial preparations of killed or modified microorganisms which can stimulate an immune response in the body in order to prevent future infection with similar microorganism. The smallpox vaccine has totally eliminated the smallpox disease from our planet. (12 Dec 1998) |
| vaccines, attenuated | Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity. (12 Dec 1998) |
| vaccines, combined | Two or more vaccines in a single dosage form. (12 Dec 1998) |
| vaccines, conjugate | Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognised by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection. (12 Dec 1998) |
| vaccines, DNA | Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers. (12 Dec 1998) |
| vaccines, inactivated | Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins. (12 Dec 1998) |
| vaccines, synthetic | Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified. (12 Dec 1998) |