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MIP <cytokine> A chemokine that is chemotactic for neutrophils and monocytes, stimulates macrophages, and may play a role in regulating haematopoiesis. Its two variants, mip-1alpha and mip-1beta, are 60% homologous to each other.
They are heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of macrophages, these chemokines are produced by a variety of cell types including neutrophils, fibroblasts, and epithelial cells.
They most likely also play a significant role in respiratory tract defenses.
(20 Sep 2002)
MIP1 DNA polymerase <enzyme> From saccharomyces cerevisiae; has structural similarity with the E coli DNA polymerase i-type enzymes
Registry number: EC 2.7.7.-
Synonym: mip1 gene product
(26 Jun 1999)
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