| MHC |
major histocompatibility complex.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| MHC r. |
the phenomenon of certain cell–cell interactions in the immune response occurring only between cells haploidentical for a major histocompatibility complex (MHC). Helper T cells are activated by antigen only when the antigen is “seen” in conjunction with self class II MHC antigens (Ia antigens in mice, HLA-DR antigens in humans) as is the case when antigen is presented by macrophages. Cytotoxic T cells are activated by and kill only cells displaying foreign antigens (e.g., viral antigens or tumor antigens) plus self class I MHC antigens (K or D antigens in mice, HLA-A, -B, or -C antigens in humans).
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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