| Mev | Symbol for 1 million electron-volts. (05 Mar 2000) |
|---|---|
| mevalonate | The salt or ester of mevalonic acid. Mevalonate kinase, an enzyme that catalyses the reaction of mevalonate and ATP to form ADP and mevalonate 5-phosphate; this enzyme participates in the pathway for steroid synthesis; a deficiency of this enzyme will lead to mevalonic aciduria and lack of development. (05 Mar 2000) |
| mevalonic acid | <chemical> Chemical name: Pentanoic acid, 3,5-dihydroxy-3-methyl- (12 Dec 1998) |
| mevalonic aciduria | Elevated levels of mevalonic acid in the urine; associated with a deficiency of mevalonate kinase. (05 Mar 2000) |
| mevastatin | Fungal metabolite which is a potent inhibitor of HMG-CoA reductase, the rate-controlling enzyme in cholesterol biosynthesis. The drug, similar to lovastatin, pravastatin and simvastatin, is used in the treatment of hyperlipidemia. (05 Mar 2000) |
| mevastatin hydroxylase | <enzyme> Hydroxylates ml-236b (mevastatin) to pravastatin; requires NADH-cytochrome p-450 reductase Registry number: EC 1.14.13.- Synonym: cytochrome p-450sca monoxygenase, cytochrome p-450(sca) (26 Jun 1999) |
| mevinolin | Intermediate in terpene synthesis, an analogue of compactin, a fungal metabolite that is used to lower plasma low density lipoprotein levels. It acts as an inhibitor of HMG CoA reductase, the rate controlling enzyme in cholesterol biosynthesis. (18 Nov 1997) |
| mevinphos | <chemical> An organophosphate cholinesterase inhibitor that is used as an insecticide. Pharmacological action: cholinesterase inhibitor, insecticide, organophosphate. Chemical name: 2-Butenoic acid, 3-((dimethoxyphosphinyl)oxy)-, methyl ester (12 Dec 1998) |