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DRG <abbreviation> Diagnosis-related group.
(05 Mar 2000)
outliers, drg In health care reimbursement, especially in the prospective payment system, those patients who require an unusually long hospital stay or whose stay generates unusually high costs.
(12 Dec 1998)
active methionine S-(5'-deoxy-5'-adenosyl)-l-methionine;condensation product of adenosine and l-methionine involving replacement of the -OPO3H2 of adenylic acid by -S+ (CH3)CH2CH2CH(NH3+)CO 2 of methionine; a sulfonium compound bearing a methyl group that is transferred in transmethylation reactions.
See: methionine adenosyltransferase.
Synonym: active methionine.
Acronym: SAM
(05 Mar 2000)
methionine <biochemistry> Contains the SCH3 group that can act as a methyl donor (see S adenosyl methionine). Common in proteins but at low frequency. The met x linkage is subject to specific cleavage by cyanogen bromide.
See: formyl peptides.
(18 Nov 1997)
methionine acetyltransferase <enzyme> Catalyses the amino-terminal acetylation
Registry number: EC 2.3.1.-
Synonym: methionine n(alpha)-acetyltransferase
(26 Jun 1999)
methionine-activating enzyme <enzyme> An enzyme that catalyses the synthesis of s-adenosylmethionine from methionine and ATP.
Chemical name: ATP:L-methionine S-adenosyltransferase
Registry number: EC 2.5.1.6
(12 Dec 1998)
methionine adenosyltransferase <enzyme> An enzyme that catalyses the synthesis of s-adenosylmethionine from methionine and ATP.
Chemical name: ATP:L-methionine S-adenosyltransferase
Registry number: EC 2.5.1.6
(12 Dec 1998)
methionine decarboxylase <enzyme> From fern dryopteris filix-mas; pyridoxal 5'-phosphate required for activity; converts methionine to 3-(methylthio)propionaldehyde
Registry number: EC 4.1.1.57
Synonym: l-methionine decarboxylase
(26 Jun 1999)
methionine malabsorption syndrome <syndrome> An inherited disorder in which there is an inability to absorb l-methionine from the gut.
(05 Mar 2000)
methionine puddle <biochemistry> A term used to describe a region of a protein surface composed of a cluster of methionine side chains. Proposed as the active hydrophobic site of calmodulin and also of signal recognition particle (SRP). The concept is of a highly fluid hydrophobic patch.
(18 Nov 1997)
methionine S-methyltransferase <enzyme> Catalyses synthesis of s-methylmethionine from l-methionine and s-adenosylmethionine
Registry number: EC 2.1.1.12
Synonym: s-adenosyl-l-methionine - l-methionine s-methyltransferase
(26 Jun 1999)
methionine sulfoxide reductase <enzyme> Do not confuse with msra gene product from staphylococcus
Registry number: EC 1.-
Synonym: msra gene product, e. Coli, peptide methionine sulfoxide reductase, peptide msra gene product
(26 Jun 1999)
methionine sulfoxime A toxic derivative of methionine formed when proteins containing it are treated with nitrogen chloride to give -SO(NH)CH3 in place of -SCH3.
(05 Mar 2000)
methionine sulfoximine <chemical> Chemical name: Butanoic acid, 2-amino-4-(S-methylsulfonimidoyl)-
(12 Dec 1998)
methionine synthase Tetrahydropteroylglutamate methyltransferase; methionine-homocysteine methyltransferase;an enzyme that catalyses the reaction of N5-methyltetrahydrofolate with l-homocysteine to form tetrahydrofolate and l-methionine; a cobalamin-requiring enzyme; a deficiency of this enzyme results in an accumulation of l-homocysteine and neurological abnormalities.
Synonym: tetrahydrofolate methyltransferase.
(05 Mar 2000)
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