| methionine | <biochemistry> Contains the SCH3 group that can act as a methyl donor (see S adenosyl methionine). Common in proteins but at low frequency. The met x linkage is subject to specific cleavage by cyanogen bromide. See: formyl peptides. (18 Nov 1997) |
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| methionine acetyltransferase | <enzyme> Catalyses the amino-terminal acetylation Registry number: EC 2.3.1.- Synonym: methionine n(alpha)-acetyltransferase (26 Jun 1999) |
| methionine adenosyltransferase | <enzyme> An enzyme that catalyses the synthesis of s-adenosylmethionine from methionine and ATP. Chemical name: ATP:L-methionine S-adenosyltransferase Registry number: EC 2.5.1.6 (12 Dec 1998) |
| methionine decarboxylase | <enzyme> From fern dryopteris filix-mas; pyridoxal 5'-phosphate required for activity; converts methionine to 3-(methylthio)propionaldehyde Registry number: EC 4.1.1.57 Synonym: l-methionine decarboxylase (26 Jun 1999) |
| methionine malabsorption syndrome | <syndrome> An inherited disorder in which there is an inability to absorb l-methionine from the gut. (05 Mar 2000) |
| methionine puddle | <biochemistry> A term used to describe a region of a protein surface composed of a cluster of methionine side chains. Proposed as the active hydrophobic site of calmodulin and also of signal recognition particle (SRP). The concept is of a highly fluid hydrophobic patch. (18 Nov 1997) |
| methionine S-methyltransferase | <enzyme> Catalyses synthesis of s-methylmethionine from l-methionine and s-adenosylmethionine Registry number: EC 2.1.1.12 Synonym: s-adenosyl-l-methionine - l-methionine s-methyltransferase (26 Jun 1999) |
| methionine sulfoxide reductase | <enzyme> Do not confuse with msra gene product from staphylococcus Registry number: EC 1.- Synonym: msra gene product, e. Coli, peptide methionine sulfoxide reductase, peptide msra gene product (26 Jun 1999) |
| methionine sulfoxime | A toxic derivative of methionine formed when proteins containing it are treated with nitrogen chloride to give -SO(NH)CH3 in place of -SCH3. (05 Mar 2000) |
| methionine sulfoximine | <chemical> Chemical name: Butanoic acid, 2-amino-4-(S-methylsulfonimidoyl)- (12 Dec 1998) |
| methionine synthase | Tetrahydropteroylglutamate methyltransferase; methionine-homocysteine methyltransferase;an enzyme that catalyses the reaction of N5-methyltetrahydrofolate with l-homocysteine to form tetrahydrofolate and l-methionine; a cobalamin-requiring enzyme; a deficiency of this enzyme results in an accumulation of l-homocysteine and neurological abnormalities. Synonym: tetrahydrofolate methyltransferase. (05 Mar 2000) |
| methionine-activating enzyme | <enzyme> An enzyme that catalyses the synthesis of s-adenosylmethionine from methionine and ATP. Chemical name: ATP:L-methionine S-adenosyltransferase Registry number: EC 2.5.1.6 (12 Dec 1998) |
| methionine-trna ligase | <enzyme> An enzyme that activates methionine with its specific transfer RNA. Chemical name: L-Methionine:tRNA(Met) ligase (AMP-forming) Registry number: EC 6.1.1.10 (12 Dec 1998) |
| active methionine | S-(5'-deoxy-5'-adenosyl)-l-methionine;condensation product of adenosine and l-methionine involving replacement of the -OPO3H2 of adenylic acid by -S+ (CH3)CH2CH2CH(NH3+)CO 2 of methionine; a sulfonium compound bearing a methyl group that is transferred in transmethylation reactions. See: methionine adenosyltransferase. Synonym: active methionine. Acronym: SAM (05 Mar 2000) |
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| cytochrome C-methionine methyltransferase | <enzyme> Forms s-methylmethionine Registry number: EC 2.1.1.- Synonym: cyt c-met methyltransferase (26 Jun 1999) |
| S-adenosyl-l-methionine | S-(5'-deoxy-5'-adenosyl)-l-methionine;condensation product of adenosine and l-methionine involving replacement of the -OPO3H2 of adenylic acid by -S+ (CH3)CH2CH2CH(NH3+)CO 2 of methionine; a sulfonium compound bearing a methyl group that is transferred in transmethylation reactions. See: methionine adenosyltransferase. Synonym: active methionine. Acronym: SAM (05 Mar 2000) |
| S-adenosyl-L-methionine-2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase | <enzyme> Proposed pathway for final reaction in ubiquinone biosynthesis. Registry number: EC 2.1.1.- Synonym: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase, ubig gene product, ubig protein (26 Jun 1999) |
| S-adenosyl-L-methionine-macrocin O-methyltransferase | <enzyme> Requires mg(ii) and s-adenosyl-l-methionine; specifically converts macrocin to tylosin by o-methylation at 3'''-position of macrocin Registry number: EC 2.1.1.- Synonym: macrocin o-methyltransferase, macrocin o-mt (26 Jun 1999) |
| S-adenosyl-L-methionine-norcoclaurine 6-O-methyltransferase | <enzyme> Catalyses the transfer of the s-methyl group of s-adenosyl-l-methionine to the 6-hydroxy group of norcoclaurine to produce coclaurine toward the synthesis of berberine in coptis japonica Registry number: EC 2.1.1.- Synonym: norcoclaurine 6-o-methyltransferase (26 Jun 1999) |
| S-adenosyl-L-methionine - scoulerine-9-O-methyltransferase | <enzyme> Catalyses the transfer of the s-methyl group of s-adenosyl-l-methionine to the 9-hydroxyl group of scoulerine during the biosynthesis of berberine; from cultured cells of coptis japonica; genbank d29809 Registry number: EC 2.1.1.- Synonym: adenosyl-met-smt, scoulerine 9-o-methyltransferase (26 Jun 1999) |
| S-adenosyl methionine thioether S-methyltransferase | <enzyme> 30,000 da enzyme methylates selenium in dimethylselenide, tellurium in dimethyltelluride, sulfur in dimethylsulfide and other thio ethers. Registry number: EC 2.1.1.- Synonym: dimethyl selenide methyltransferase, thioether methyltransferase (26 Jun 1999) |
| enkephalin, methionine | <chemical> Endogenous pentapeptide with morphine-like activity. The amino acid in position 5 is methionine. Chemical name: Adrenorphin (human), 6-de-L-arginine-7-de-L-arginine-8-de-L-valinamide- (12 Dec 1998) |
| L-methionine gamma-lyase | <enzyme> Pharmacological action: antimetabolites, antineoplastic Registry number: EC 4.4.1.11 Synonym: l-methionine alpha-deamino gamma-mercaptomethane-lyase, methionine dethiomethylase, l-methioninase, methioninase (26 Jun 1999) |