| met | 1. <oncogene> An oncogene, identified in mouse osteosarcoma. 2. <chemistry> Having less than the highest number of hydroxyl groups; said of acids; as, metaphosphoric acid. Also used adjectively. (04 Mar 1998) |
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| met enkephalin | <protein> See enkephalins. (18 Nov 1997) |
| met repressor operator complex | Repressor protein, 104 residues, product of the metJ gene, which regulates methionine biosynthesis in E. Coli. Dimeric molecules bind to adjacent sites 8 base pairs apart on the DNA, sequence recognition is by interaction between antiparallel strands of protein and the major groove of the B form DNA duplex. (18 Nov 1997) |
| Met-enkephalin heptapeptide dipeptidase | <enzyme> Enzyme from rabbit ear artery forms met-enkephalin from met(5)-enkephalin-arg(6)-phe(7); inhibited by captopril Registry number: EC 3.4.15.- Synonym: met-enkephalin-arg(6)-phe(7) cleavage enzyme, me-ap dipeptidase (26 Jun 1999) |
| meta- | 1. In medicine and biology, a prefix denoting the concept of after, subsequent to, behind, or hindmost. Compare: post-. 2. In chemistry, an italicised prefix denoting joint, action sharing. 3 (m-). In chemistry, an italicised prefix denoting compound formed by two substitutions in the benzene ring separated by one carbon atom, i.e., linked to the first and third, second and fourth, etc., carbon atoms of the ring. For terms beginning with meta-, or m-, see the specific name. Origin: G. After, between, over (05 Mar 2000) |
| meta-analysis | <statistics> A quantitative method of combining the results of independent studies (usually drawn from the published literature) and synthesizing summaries and conclusions which may be used to evaluate therapeutic effectiveness or to plan new studies. With application chiefly in the areas of research and medicine. It is often an overview of clinical trials. It is usually called a meta-analysis by the author or sponsoring body and should be differentiated from reviews of the literature. (27 Jun 1999) |
| metabasis | Rarely used term for a change of any kind in symptoms or course of a disease. Origin: G. A passing over, change, fr. Metabaino, to pass over (05 Mar 2000) |
| metabiosis | Dependence of one organism on another for its existence. See: commensalism, mutualism, parasitism. Origin: meta-+ G. Biosis, way of life (05 Mar 2000) |
| metabisulfite test | A test for sickle cell haemoglobin (Hb S); deoxygenation of cells containing Hb S is enhanced by addition of sodium metabisulfite to the blood, causing sickling visible on a slide; certain other abnormal haemoglobins (Hb CHarlem and Hb I) also sickle in this test. (05 Mar 2000) |
| metabisulphite | <chemistry> A group of compounds used as food and drug preservatives that is known to evoke a severe allergic response in sensitive individuals. Symptoms may include rash, urticaria, angioedema, wheezing or low blood pressure. (04 Mar 1998) |
| metabole | <medicine> A change or mutation; a change of disease, symptoms, or treatment. Origin: NL, from Gr. Change; beyond + to throw. Source: Websters Dictionary (01 Mar 1998) |
| metabolia | <zoology> A comprehensive group of insects, including those that undegro a metamorphosis. Source: Websters Dictionary (01 Mar 1998) |
| metabolian | <zoology> An insect which undergoes a metamorphosis. Source: Websters Dictionary (01 Mar 1998) |
| metabolic | 1. <biology> Of or pertaining to metamorphosis; pertaining to, or involving, change. 2. <physiology> Of or pertaining to metabolism; as, metabolic activity; metabolic force. Source: Websters Dictionary (01 Mar 1998) |
| metabolic acidosis | <biochemistry> A metabolic derangement of acid-base balance where the blood pH is abnormally low. Causes include haemorrhagic shock, cardiogenic shock, severe dehydration, sepsis, toxic ingestion (for example isopropyl alcohol, methanol), alcoholic ketoacidosis, lactic acidosis, renal failure and diabetic ketoacidosis. Respiratory acidosis will occur if the lungs are not ventilating properly. (27 Jun 1999) |
| RNA, transfer, met | A transfer RNA which is specific for carrying methionine to sites on the ribosomes in preparation for protein elongation. Initiation of protein synthesis uses trna(f)met in prokaryotic cells and trna(I)met in eukaryotic cells. (12 Dec 1998) |
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| proto-oncogene proteins c-met | <enzyme> A transmembrane tyrosine kinase that is the receptor for hepatocyte growth factor (scatter factor). It consists of an extracellular alpha chain which is disulfide linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and critical sites for the regulation of kinase activity. Registry number: EC 2.7.11.- (12 Dec 1998) |