| mepacrine hydrochloride | An acridine derivative, C23H30ClN3O-2HCl-2H2O, used as an antimalarial that destroys the trophozoites of Plasmodium vivax and P. Falciparum, but does not affect the gametocytes, sporozoites, or exoerythrocytic stage of parasites; also used as an anthelmintic. As a dihydrochloride, it is used as a stain in cytogenetics to demonstrate Y chromatin by fluorescent microscopy. Quinacrine hydrochloride intercalates with DNA and also uncouples oxidative and photophosphorylation. Synonym: atebrine hydrochloride, mepacrine hydrochloride. (05 Mar 2000) |
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| mepartricin | <chemical> Polyene macrolide antibiotic with unknown composition. It is obtained from streptomyces aureofaciens. It is used as an antifungal agent, an antiprotozoal agent, and in the treatment of benign prostatic hypertrophy. Pharmacological action: antibiotics, antifungal, antibiotics, macrolide, antiprotozoal agents. Chemical name: Partricin, methyl ester (12 Dec 1998) |
| mepazine acetate | 10-[(1-Methyl-3-piperidyl)methyl]phenothiazine acetate;a phenothiazine derivative with actions and uses similar to those of chlorpromazine. Also available as mepazine acetate hydrochloride. (05 Mar 2000) |
| mepenzolate bromide | N-Methyl-3-piperidyl benzilate methyl bromide;an anticholinergic drug. (05 Mar 2000) |
| meperidine | <chemical> 1-methyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester. A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labour. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration. Pharmacological action: analgesics, opioid, anaesthesia adjuvants, narcotics. Chemical name: 4-Piperidinecarboxylic acid, 1-methyl-4-phenyl-, ethyl ester (12 Dec 1998) |
| meperidine hydrochloride | Ethyl 1-methyl-4-phenylisonipecotate hydrochloride;a widely used narcotic analgesic. Synonym: pethidine. (05 Mar 2000) |
| mephenesin | <chemical> A centrally acting muscle relaxant with a short duration of action. Pharmacological action: muscle relaxants, central. Chemical name: 1,2-Propanediol, 3-(2-methylphenoxy)- (12 Dec 1998) |
| mephenoxalone | 5-[(o-Methoxyphenoxy)methyl]-2-oxazolidinone;a mild tranquilliser and muscle relaxant. (05 Mar 2000) |
| mephentermine | <chemical> A sympathomimetic agent with mainly indirect effects on adrenergic receptors. It is used to maintain blood pressure in hypotensive states, for example, following spinal anaesthesia. Although the central stimulant effects of mephentermine are much less than those of amphetamine, its use may lead to amphetamine-type dependence. Pharmacological action: adrenergic alpha-agonists, adrenergic agents, sympathomimetic, vasoconstrictor agents. Chemical name: Benzeneethanamine, N,alpha,alpha-trimethyl- (12 Dec 1998) |
| mephenytoin | <chemical> An anticonvulsant effective in grand mal epilepsy. It may cause blood dyscrasias. Pharmacological action: anticonvulsants. Chemical name: 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl- (12 Dec 1998) |
| mephitic | Foul, poisonous, or noxious. Origin: L. Mephitis, a noxious exhalation (05 Mar 2000) |
| mephitical | 1. Tending to destroy life; poisonous; noxious; as, mephitic exhalations; mephitic regions. 2. Offensive to the smell; as, mephitic odors. <chemistry> Mephitic air, carbon dioxide; so called because of its deadly suffocating power. See Carbonic acid, under Carbonic. Origin: L. Mephiticus, fr. Mephitis mephitis: cf. F. Mephitique. Source: Websters Dictionary (01 Mar 1998) |
| mephitis | 1. Noxious, pestilential, or foul exhalations from decomposing substances, filth, or other source. 2. <zoology> A genus of mammals, including the skunks. Origin: L. Mephitis: cf. F. Mephitis. Source: Websters Dictionary (01 Mar 1998) |
| mephobarbital | <chemical> A barbiturate that is metabolised to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital. Pharmacological action: anticonvulsants, gaba modulators, sedatives, barbiturate. Chemical name: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-1-methyl-5-phenyl- (12 Dec 1998) |
| mepivacaine | <chemical> A local anaesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anaesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. Pharmacological action: anaesthetics, local. Chemical name: 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl- (12 Dec 1998) |