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Meltzer-Lyon test A test used in diagnosis of gallbladder conditions: 25 ml of a 25% solution of magnesium sulfate are delivered into the region of the sphincter of Oddi through a duodenal tube, causing contraction of the gallbladder, relaxation of the sphincter, and the expulsion of bile from the common duct and gallbladder; bile from the common duct is relatively pale and is expelled first, that from the gallbladder follows; samples aspirated from the tube are examined for pus cells, pigment granules, epithelial cells, cholesterol, etc.
(05 Mar 2000)
Lyon, B <person> Vincent, U.S. Physician, 1880-1953.
See: Meltzer-Lyon test.
(05 Mar 2000)
Lyon hypothesis <genetics> Hypothesis, first advanced by Lyon, concerning the random inactivation of one of the two X chromosomes of the cells of female mammals.
In consequence females are chimaeric for the products of the X chromosomes, a situation that has been exploited in female Negroes (who are heterotypic for isozymes of glucose 6 phosphate dehydrogenase) as a means to confirm the monoclonal origin of papillomas and of atherosclerotic plaques.
(20 Mar 1998)
Lyon, Mary <person> English cytogeneticist, *1925.
See: Lyon hypothesis, lyonization.
(05 Mar 2000)
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