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"Lovastatin Tab. Kolmar"에 대한 영영 의학사전 세부 검색 결과입니다
CancerWEB 영영 의학사전 유사 검색 결과 : 2 페이지: 1
TAB vaccine A suspension of killed typhoid and paratyphoid A and B bacilli.
See: typhoid vaccine.
Synonym: TAB vaccine.
(05 Mar 2000)
lovastatin <chemical> A fungal metabolite isolated from cultures of aspergillus terreus. The compound is a potent anticholesteraemic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme a reductase (hydroxymethylglutaryl CoA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver. Several studies have shown that because of its enzyme inhibitory activity it acts as an antineoplastic agent for certain tumours.
Pharmacological action: anticholesteraemic agents, antineoplastic agent, hydroxymethylglutaryl-CoA reductase inhibitors.
Chemical name: Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))-
(12 Dec 1998)
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