| loperamide | <chemical> 4-(p-chlorophenyl)-4-hydroxy-n.n-dimethyl-alpha,alpha-diphenyl-1-piperidine butyramide hydrochloride. Synthetic anti-diarrhoeal agent with a long duration of action; it is not significantly absorbed from the gut, has no effect on the adrenergic system or central nervous system, but may antagonise histamine and interfere with acetylcholine release locally. Pharmacological action: antidiarrhoeals. Chemical name: 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl- (12 Dec 1998) |
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| loperamide hydrochloride | 4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-a,alpha-diphenyl-1-piperidinebutyramide monohydrochloride;an antiperistaltic agent used to treat diarrhoea. (05 Mar 2000) |