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apoB 100 apolipoprotein B100
apolipoprotein B-100 <biochemistry> An apolipoprotein found in LDL, VLDL, and IDL. The ligand for the LDL receptor; absent in certain types of abetalipoproteinaemia.
Apolipoproteins are proteins on the surface of the lipoprotein complex that bind to specific enzymes or transport proteins across the cell membrane.
The normal range is 40 to 125 mg/dl.
Elevated levels may be seen in familial combined hyperlipidaemia and acquired hyperlipidaemia. Elevation may also be seen in cases of acute angina and myocardial infarction.
(27 Sep 1997)
nerve tissue protein s 100 Highly acidic calcium-binding protein found in large concentration in the brain and believed to be glial in origin; also found in other organs in the body.
(12 Dec 1998)
invariant surface glycoprotein 100 <chemical> A stage-specific invariant surface protein in trypanosoma brucei containing an internal, serine-rich, repetitive motif; amino acid sequence given in first source; genbank y14833
Synonym: isg-100
(05 Dec 1998)
Triton X 100 <chemical> Nonionic detergent used in isolating membrane proteins: the detergent replaces the phospholipids that normally surround such a protein.
Other detergents of the Triton group are occasionally used so the full name should be quoted.
(18 Nov 1997)
Aeromonas hydrophilia lipase-acyltransferase <enzyme> A member of the lipase family; a distinct group of lipolytic enzymes which have a novel active site structure
Registry number: EC 3.1.1.-
Synonym: gcat
(26 Jun 1999)
diacylglycerol lipase <enzyme> An enzyme of the hydrolase class that catalyses the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinaemia type I.
Chemical name: Triacylglycero-protein acylhydrolase
Registry number: EC 3.1.1.34
(12 Dec 1998)
diglyceride lipase <enzyme> An enzyme of the hydrolase class that catalyses the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinaemia type I.
Chemical name: Triacylglycero-protein acylhydrolase
Registry number: EC 3.1.1.34
(12 Dec 1998)
familial lipoprotein lipase deficiency An rare inherited disorder where there is a deficiency of an enzyme (lipoprotein lipase) which breaks down fat molecules, causing the accumulation of fats or lipoproteins in the blood.
Symptoms in infancy include abdominal pain (appears as if its colic), failure to thrive and skin lesions (xanthomas).
(27 Sep 1997)
familial lipoprotein lipase inhibitor An inhibitor found in certain individuals that inhibits lipoprotein lipase resulting in accumulation of chylomicrons, VLDL, and triacylglycerols; similar in symptoms to familial lipoprotein lipase deficiency.
(05 Mar 2000)
lipase <enzyme> An enzyme that catalyses the hydrolysis of fats (monoglycerides, diglycerides and triglycerides) to glycerol and fatty acids. Calcium ions are usually required.
(13 Nov 1997)
lipase test A diagnostic test based on the measurement of lipase in blood and urine as an indicator of pancreatic disease.
(05 Mar 2000)
lipoprotein lipase <enzyme> An enzyme of the hydrolase class that catalyses the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinaemia type I.
Chemical name: Triacylglycero-protein acylhydrolase
Registry number: EC 3.1.1.34
(12 Dec 1998)
lipoprotein lipase deficiency, familial A rare familial condition characterised by massive chylomicronaemia and decreased levels of other lipoproteins. It is due to deficiency of lipoprotein lipase, an alkaline triglyceride hydrolase which catalyses an important step in the extrahepatic removal of triglyceride-rich lipoproteins from the blood.
(12 Dec 1998)
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