| sertoli-leydig cell tumour | An ovarian tumour usually of low-grade malignancy occurring most frequently in the third and fourth decades, with 75% seen in women under 40. It is rare, representing less than .02% of ovarian cancers. The tumour typically produces androgens with virilization being noted in 70-85% of the patients. (holland et al., cancer medicine, 3d ed, p1684) (12 Dec 1998) |
|---|---|
| Leydig cell | Interstitial cells of the mammalian testis, involved in synthesis of testosterone. (18 Nov 1997) |
| Leydig cell adenoma | <tumour> A small benign tumours of the testis that often produce testosterone, causing endocrine symptoms. Synonym: interstitial cell tumour of testis. (05 Mar 2000) |
| leydig cell tumour | The most common nongerminal tumour of the testis, derived from the leydig cells. It is rarely malignant. This tumour appears among 1-3% of testicular tumours and although they may be seen in children, the median age of appearance is 60 years. They are sometimes seen in women as ovarian tumours. Clinically, symptoms are usually related to the endocrine abnormalities induced by this tumour. (12 Dec 1998) |
| tumor | 1. <oncology> An abnormal mass of tissue that results from excessive cell division that is uncontrolled and progressive, also called a neoplasm. Tumours perform no useful body function. They may be either benign (not cancerous) or malignant. 2. Swelling, one of the cardinal signs of inflammations, morbid enlargement. Origin: L. Tumere = to swell (12 May 1997) |
| tumor marker | <investigation, oncology> A substance in the body that usually indicates the presence of cancer. These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples. Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH). They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids. (18 Jul 2002) |
| tumor necrosis factor | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |
| Leydig | Franz von, German anatomist, 1821-1908. See: Leydig's cells, Leydig cell adenoma. (05 Mar 2000) |
| leydig cells | Cells in the interstitial tissue of the testis that are believed to furnish the internal secretion of that gland. (12 Dec 1998) |
| Leydig, Franz von | <person> In 1855 was appointed Professor of Histology in Wurzburg and later in Tubingen and Bonn. Was the founder of Comparative Histology. Leydig's Cells - interstitial cells of the testis. Lived: 1821-1908. B. Rothenburg, May 21st, 1821, d. Apr 13th, 1908. (05 Dec 1998) |
| Leydig's cells | lutropin |
| T-cell-rich, B-cell lymphoma | <tumour> A B-cell lymphoma in which more than 90% of the cells are of T-cell origin, masking the large cells that form the neoplastic B-cell component. See: adult T-cell lymphoma. (05 Mar 2000) |
| absorption cell | A small glass chamber with parallel sides, in which absorption spectra of solutions can be obtained. (05 Mar 2000) |
| acid cell | One of the cell's of the gastric glands; it lies upon the basement membrane, covered by the chief cell's, and secretes hydrochloric acid that reaches the lumen of the gland through fine intracellular and intercellular canals (canaliculi). Synonym: acid cell, oxyntic cell. (05 Mar 2000) |
| acidophil cell | A cell whose cytoplasm or its granules stain with acid dyes. (05 Mar 2000) |