| Lesch, Michael | <person> U.S. Paediatrician, *1939. See: Lesch-Nyhan syndrome. (05 Mar 2000) |
|---|
| Lesch-Nyhan disease | <syndrome> A sex-linked recessive inherited disease in humans that results from mutation in the gene for the purine salvage enzyme hypoxanthine phosphoribosyltransferase (HGPRT), located on the X chromosome. Results in severe mental retardation. It is characterised by physical and mental retardation, and distressing behavioural abnormalities, such as compulsive self mutilation, hyperuricaemia, and choreoathetosis, and renal failure. Excess uric acid production exists due to the absence of an enzyme essential to purine metabolism. Inheritance: sex-linked recessive. (22 Sep 2002) |
|---|---|
| Lesch-Nyhan syndrome | <syndrome> A sex-linked recessive inherited disease in humans that results from mutation in the gene for the purine salvage enzyme hypoxanthine phosphoribosyltransferase (HGPRT), located on the X chromosome. Results in severe mental retardation. It is characterised by physical and mental retardation, and distressing behavioural abnormalities, such as compulsive self mutilation, hyperuricaemia, and choreoathetosis, and renal failure. Excess uric acid production exists due to the absence of an enzyme essential to purine metabolism. Inheritance: sex-linked recessive. (22 Sep 2002) |
| Brescia, Michael | <person> U.S. Nephrologist, *1933. See: Brescia-Cimino fistula. (05 Mar 2000) |
| chalcone michael allen | An organic molecule prepared by aldol condensation of acetophenone andbenzaldehyde. (09 Oct 1997) |
| Wells, Michael Vernon | <person> 20th century English physician. See: Muckle-Wells syndrome. (05 Mar 2000) |
| DeBakey, Michael Ellis | <person> U.S. Heart surgeon, *1908. See: DeBakey's classification, DeBakey forceps. (05 Mar 2000) |
| O'Hara, Michael Jr | <person> U.S. Surgeon, 1869-1926. See: O'Hara forceps. (05 Mar 2000) |
| Epstein, Michael Anthony | <person> English virologist, *1921. See: Epstein-Barr virus. (05 Mar 2000) |
| Faraday, Michael | <person> English physicist and chemist, 1791-1867. See: farad, faraday, Faraday's constant, Faraday's laws. (05 Mar 2000) |
| Lenhossek, Michael von | <person> Hungarian anatomist, 1863-1937. See: Lenhossek's processes. (05 Mar 2000) |
| Leventhal, Michael | <person> U.S. Obstetrician-gynecologist, 1901-1971. See: Stein-Leventhal syndrome. (05 Mar 2000) |