| Leber's hereditary optic atrophy | Hereditary degeneration of the optic nerve and papillomacular bundle with resulting rapid loss of central vision, progressive for several weeks, then usually stationary with permanent central scotoma; age of onset is variable, most often in the third decade; more males than females are affected and transmission is cytoplasmic and strictly on the female side. Mutation on the mitochondrial chromosome involved, which presumably interacts with an X-linked mutant. This mechanism may explain the bizarre sex ratio, which differs significantly from one country to another. (05 Mar 2000) |
|---|---|
| Leber's idiopathic stellate neuroretinitis | A unilateral neuroretinitis with perifoveal exudates in Henle's nerve fibre layer producing a macular star and spontaneous regression in a few months. Synonym: Leber's idiopathic stellate neuroretinitis. (05 Mar 2000) |
| Leber's idiopathic stellate retinopathy | An inflammation affecting the optic nerve head and the posterior pole of the retina, with cells in the nearby vitreous, usually producing a macular star. Synonym: papilloretinitis. (05 Mar 2000) |
| Leber's plexus | A small venous plexus in the eye between the venous sinuses of the sclera (of Schlemm) and the spaces of the iridocorneal angle (of Fontana). (05 Mar 2000) |
| Leber, Theodor | <person> German ophthalmologist, 1840-1917. See: Leber's idiopathic stellate neuroretinitis, Leber's hereditary optic atrophy, Leber's plexus, amaurosis congenita of Leber. (05 Mar 2000) |
| amaurosis congenita of Leber | An autosomal recessive cone-rod abiotrophy causing blindness or severely reduced vision at birth. (05 Mar 2000) |
|---|